Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1996-05-24
1999-01-05
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
A61K 3159
Patent
active
058563172
ABSTRACT:
A method of inducing inhibition or loss of cell proliferation in solid tumors utilizing a Vitamin D.sub.3 analog, as well as a method of inducing loss of cell proliferation in solid tumors utilizing trans retinoic acid and a Vitamin D.sub.3 analog.
In another aspect, a method of inducing inhibition or loss of cell proliferation in solid tumors utilizing a Vitamin D.sub.3 metabolite, as well as a method of inducing loss of cell proliferation in solid tumors utilizing trans retinoic acid and a Vitamin D.sub.3 metabolite.
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Zhou et al., Development of a Novel 1,25(OH).sub.2 Vitamin D.sub.3 Analog with Potent Ability to Induce HL-60 Cell Differentiation Without Modulating Calcium Metabolism: Blood, vol. 78, No. 1, pp. 75-82, Jul. 1, 1991.
Dore Benoit Thomas
Momparler Richard Lewis
Uskokovic Milan Radoje
Goldberg Jerome D.
Hoffmann-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
Silverman Robert A.
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