Methods of treating tumors with compositions of catecholic butan

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – C-o-group doai

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A61K 3105

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active

050082949

ABSTRACT:
The invention relates to methods useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin comprising methods for the administration of pharmacologically active compositions containing catecholic butanes. The invention also relates to methods of preventing the occurence of tumors, and the use of catecholic butanes as a sunscreening agent. The preferred catecholic butane is nordihydroguaiaretic acid. The preferred methods of application of the compositions containing catecholic butanes are by topical application and intratumor injection.

REFERENCES:
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patent: 4695590 (1987-09-01), Lippman
"Medicine Based on a Derivative of Pyrocatechol", Special Patent for Medicine, No. 981,050 (France).
"Antipsoriatic Drugs as Inhibitors of Soybean Lipoxygenase, A Possible Mode of Action", Jagadish C. Sircar, et al., Protagladins Leucotrienes and Medicine, 1983, vol. II, 373-380.
Smart et al., Rocky Mount. Med. J., Nov. 1970, pp. 39-43.
Bhuvcineswaran et al., Biochem., 11: 85-91, 1972.

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