Methods of treating sleep disturbance

Details Methods of treating sleep disturbance Methods of treating sleep disturbance

1980-04-07

1981-09-15

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

A61K 31447

Patent

active

042897807

ABSTRACT:
Method of treating sleep disturbance which comprises administering a compound of formula ##STR1## wherein R.sub.1 is phenethyl or butyrophenone optionally mono-substituted in the phenyl ring by fluorine, chlorine, bromine or lower alkyl or alkoxy, R.sub.2 is OR.sub.5 wherein R.sub.5 is lower alkyl or alkenyl or phenyl optionally mono-substituted by fluorine, chlorine, bromine, or alkoxy; or N(R.sub.6)R.sub.7 wherein R.sub.6 and R.sub.7 are each hydrogen, lower alkyl or cycloalkylalkyl, cycloalkyl, phenyl optionally mono-substituted by fluorine, chlorine, bromine, lower alkyl or lower alkoxy or lower phenylalkyl optionally mono-substituted in the phenyl ring by fluorine, chlorine, bromine or lower alkyl or alkoxy or R.sub.6 and R.sub.7 together with the nitrogen atom to which they are bound form a saturated heterocycle of 5 to 6 ring members, and either R.sub.3 is lower alkyl or cycloalkylalkyl, cycloalkyl or phenyl optionally mono-substituted by fluorine, chlorine, bromine or lower alkyl or alkoxy or, when R.sub.1 is optionally mono-substituted phenethyl, also lower alkenyl and R.sub.4 is hydrogen or R.sub.3 and R.sub.4 together with the carbon atom to which they are bound form a C.sub.4-6 -cycloalkyl ring.

REFERENCES:
Chem. Abst. 82-156102p, (1975).

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