Methods of treating rheumatoid arthritis with an...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

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C424S130100, C424S133100, C424S152100, C424S158100, C424S172100, C514S251000, C530S387100, C530S387300, C530S388100, C530S388200, C530S388230

Reexamination Certificate

active

07846442

ABSTRACT:
Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed is a composition comprising methotrexate and an anti-tumor necrosis factor antibody. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.

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