Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-04-29
1998-10-27
Jarvis, William R. A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3140
Patent
active
058278745
ABSTRACT:
Methods of using proline for the treatment of inflammation and pain and especially for the treatment of inflammatory conditions, rheumatic and non-rheumatic pain and for postoperative or posttraumatic pain, are described.
REFERENCES:
patent: 3932638 (1976-01-01), Coirre et al.
patent: 4414202 (1983-11-01), Silvetti
patent: 5198465 (1993-03-01), Dioguardi
Jemec and Moe, 1996, "Topical Treatment of Skin Ulcers in Prolidase Deficiency", Ped. Dermatol. 13:58-60.
Arata et al., 1986, "Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency", Arch. Dermatol. 122:626-627.
Meyers et al., 1979, "The Effect of Selected Amino Acids on Gelatin-Induced Inflammation in Adult Male Mice", Inflammation 3:225-233.
Chvapil, 1975, "Pharmacology of Fibrosis: Definitions, Limits and Perspectives", Life Sciences 16:1345-1361.
Geistlich, Chemical Abstracts, vol. 96, abstract No. 168773, Jan. 1982.
Lutostanska et al., 1993, "A Search for New Active Amino Acids Responsible for Pharmacological Activity of Collagen Degradation Products", Pol. J. Pharmacol. 45:253-268.
Budavari et al., 1989. The Merck Index (Merck & Co., Inc., Rahway, New Jersey) pp. 769, 1092, 1098, 1183-1184, 1236 and 1272-1273.
Sarhan and Seiler, 1989, "Proline and Proline Derivatives as Anticonvulsants", Gen. Pharmac. 20:53-60.
Negwer, 1987, Organic-Chemical Drugs and their Synonyms (Akademie-Verlag Berlin) pp. 49, 53 and 141.
Hayasaka et al., 1985, "Clinical Trials of Vitamin B.sub.8 and Proline Supplementation for Gyrate Atrophy of the Choroid and Retina", Brit. J. Opthamol. 69:283-290.
Schubotz and Hausmann, 1977, "Treatment of Degenerative Arthropathies with N-Acetyl-Hydroxyproline", Therapiewoche 27:4248-4252.
Jacotot et al., 1971, "Prevention of Certain Acute and Chronic Effects of Nicotine by N-Acetyl-Hydroxyproline", Pathologie Biologie 19:497-502.
Huriez and Simon-Thery, 1971, "Action of a Derivative of Hydroxyproline--Specifically Contained in Collagen--in Cecatrization of Ulcers of the Legs", Lille Medical, 3me Serie 16:1197-1202.
Falbe and Regitz, Rompp Chemie Lexikon, 9. Ed. (Georg Thieme Verlag Stuttgart, New York) pp. 1908, 3627 and 3703, 1989.
Gerhartz et al., Ullmann's Encyclopedia of Industrial Chemistry, 5. Ed. (VCH Publishing) p. 86, 1989.
Bernhard Segesser
Meyer Hans
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