Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-01-25
2011-01-25
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S266000
Reexamination Certificate
active
07875620
ABSTRACT:
The present invention provides methods of treating microbacterial infections comprising administering to a subject in need thereof, a composition comprising a compound of formula I:wherein:X1, X2and X3are selected from the group consisting of oxygen, sulfur, aminoalkyl, alkoxy, aryl, and heteroaryl, unsubstituted or substituted; andR1, R2, R3and R4are selected from the group consisting of hydrogen, actinium, silicon, germanium, cyano, alkyl, alkoxy, allyl, alkenyl, alkynyl, alkylaryl, arylalkyl, aminoalkyl, alkylamino, alkene, alkyne, aryl, halide, alkylhalide, alkyloxyalkyl, thioalkyl, alkylthioalkyl, alkylamino, cycloalkyl, heterocyclyl, unsubstituted or substituted; or a pharmaceutically acceptable salt thereof. The present invention further provides methods of treating bacterial infections comprising administering to a subject in need thereof, an effective amount of a pharmaceutical composition comprising uric acid, urate, derivatives thereof, salts and hydrates thereof and prodrugs thereof and a pharmaceutically acceptable carrier.
REFERENCES:
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patent: WO 02/069949 (2002-09-01), None
Fan et. al., Bioorganic & Medicinal Chemistry Letters, Pergamon, vol. 7, pp. 3107-3112.
Gold, The New England Journal of Medicine, Massachusetts Medical Society, vol. 335, pp. 1445-1453.
Ruef, Infection, Urban & Vogel, vol. 6, pp. 315-327.
Horl, American Journal of Nephrology, 1999, S Karger AG, vol. 19, No. 2, pp. 111-113.
Myers Bigel & Sibley Sajovec, PA
Padmanabhan Sreeni
Pihonak Sarah
Piper Medical, Inc.
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