Methods of treating ischemic related conditions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S357000, C514S365000, C514S400000

Reexamination Certificate

active

07456179

ABSTRACT:
The present invention relates to methods of treating ischemia-related conditions by administering to a patient in need of such methods certain thiosemicarbazone compounds. Preferred embodiments of the present invention relates to methods of treating specific ischemia-related conditions, including but not limited to Alzheimer's disease, Parkinson's disease, Coronary artery bypass graft surgery, Global cerebral ischemia due to cardiac arrest, focal cerebral infarction, cerebral hemorrhage, hemorrhage infarction, hypertensive hemorrhage. hemorrhage due to rupture of intracranial vascular abnormalities, subarachnoid hemorrhage due to rupture of intracranial arterial aneurysms, hypertensive encephalopathy, carotid stenosis or occlusion leading to cerebral ischemia, cardiogenic thromboembolism, spinal stroke and spinal cord injury, diseases of cerebral blood vessels: e.g., atherosclerosis, vasculitis, Macular degeneration, myocardial infarction, cardiac ischemia and superaventicular tachyarrhytmia.

REFERENCES:
patent: 5721259 (1998-02-01), Sartorelli et al.
patent: 6911460 (2005-06-01), King et al.
patent: 2002/0188011 (2002-12-01), King et al.
patent: 2004/0038890 (2004-02-01), Aiyar et al.
patent: WO 2004/099371 (2004-11-01), None
patent: WO 2004099371 (2004-11-01), None

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