Methods of treating inflammatory dermatosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514180, 514559, 514555, A61K 3156, A61K 3120

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active

059983957

ABSTRACT:
Inflammatory dermatoses are controlled and cleared by topical application to the affected areas of the skin of a composition containing both a corticosteroid and a retinoid. The combined therapy is more effective than either active ingredient alone and is particularly effective for chronic dermatoses which are or have become resistant to corticosteroid treatment alone. After clearing has been obtained with once or twice daily applications of the corticosteroid-retinoid composition, usually after several weeks, clearance can be maintained by less frequent application or lower concentrations of the composition or by application of only one of the corticosteroid or retinoid, less potent corticosteroids, or other non-steroidal therapies, depending upon the particular dermatosis being treated.

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Kays H. Kaidbey, M.D. et al., "Treatment of Psoriasis with Topically Applied Tretinoin and Steriod Ointment," Arch Dermatol 111, pp. 1001-1003 (1975);.
P. Frost et al., "Retinoic Acid for the Therapy of Psoriasis," Acta Derma-tovener (Stockholm), Suppl. 74, pp. 155-160 (1975);.
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