Methods of treating gout with chalcone derivatives

Details Methods of treating gout with chalcone derivatives Methods of treating gout with chalcone derivatives

1988-12-14

1989-09-05

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514629, 514630, A61K 31135, A61K 3116

Patent

active

048639680

ABSTRACT:
Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used as antigout agents. The chalcone derivatives are also reported to inhibit the destruction of the myelin sheath in the central nervous system of multiple sclerosis patients and are thus useful in controlling the progressive nature of the disease.

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