Methods of treating diabetes mellitus and clycogen storage disea

Details Methods of treating diabetes mellitus and clycogen storage disea Methods of treating diabetes mellitus and clycogen storage disea

1994-12-27

1998-10-06

Prats, Francisco C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 25, 514 54, 514 61, 514866, 536 41, 536 186, 5361231, 53612313, 536123, 536 172, 25217417, A61K 3170, A61K 31705, C07H 702

Patent

active

058176349

ABSTRACT:
This present invention provides a method and compounds for priming the incorporation of cellular glucose into an oligosaccharide in a cell comprising administering to the cell a priming amount of a membrane-permeating nontoxic glycoside having a suitable hydrophobic organic group joined by a linkage to a suitable hydrophilic saccharide, wherein the hydrophilic saccharide has a nonreducing terminal sugar residue selected from the group consisting of glucose or xylose, thereby priming the incorporation of cellular glucose onto the glycoside to form an oligosaccharide. Also disclosed are methods wherein the administration of the glycoside is sufficient to treat diabetes mellitus and glycogen storage disease.

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