Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1995-06-05
1999-02-16
Leary, Louise
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 4, 435 71, 435 72, 435 721, 435 724, 4352402, 4352401, 514 1, 514885, 514863, 514580, 4241841, 4241771, 424 91, C12Q 102, C12Q 100, G01N 3353, A01N 6100
Patent
active
058719504
ABSTRACT:
The present invention provides methods for treating autoimmune diseases in mammals and for preventing or treating transplantation rejection in a transplant recipient. The methods of treatment involve the use of drugs capable of suppressing expression of MHC Class I molecules. In particular the use of the drug methimazole to suppress expression of MHC Class I molecules in the treatment of autoimmune diseases and the prevention or treatment of rejection in a transplant recipient is disclosed. In addition in vivo and in vitro assays are provided for the assessment and development of drugs capable of suppressing MHC Class I molecules.
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Kohn Leonard
Ledley Fred D.
Mozes Edna
Napolitano Giorgio
Saji Motoyasu
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