Methods of treating androgen deficiency in men using...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C514S651000

Reexamination Certificate

active

07067557

ABSTRACT:
The administration of antiestrogens to men suffering a relative androgen deficiency stimulates the body's production of testosterone leading to a correction of the deficiency. For example, male menopause, loss of cognitive function, insulin resistance, type 2 diabetes, obesity, excessive weight, Alzheimer's disease, and combinations thereof, can all be characterized by significant decreases in serum levels of bioavailable androgens. Administration of antiestrogens to men restores optimum serum levels of bioavailable androgens, and, thus, serves as a treatment for these disorders and relative androgen deficiency in general.

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Basaria, et al. Risks Versus Benefits of Testosterone Therapy in Elderly Men, Drugs & Aging, 1999, Aug.; 15(7); 131-142.
Lund, et al. “Testosterone and Andropause: The Feasibility of Testosterone Replacement Therapy in Elderly Men.” Pharmacotherapy, vol. 19, No. 8, 1999; 951-956.
The Merck Manual, 14th ed., published 1982 by Merck Sharpe & Dohme Research Laboratories, pp. 916-921.

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