Methods of treating and detecting cancer using viruses

Details Methods of treating and detecting cancer using viruses Methods of treating and detecting cancer using viruses

2006-06-06

2006-06-06

Housel, James (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S005000, C435S007200, C424S130100, C424S138100, C424S155100, C424S277100, C424S281100, C424S184100, C436S064000

Reexamination Certificate

active

07056689

ABSTRACT:
The invention provides a method of treating cancer in a mammal comprising administering to the mammal an effective amount of virus, particularly Newcastle Disease Virus or other Paramyxovirus. The invention also provides a method of treating cancer in a mammal comprising administering such viruses to the mammal in combination with another agent such as a chemotherapeutic compound, immunoadjuvant, cytokine, or immunosuppressive agent. The invention further provides a method of detecting cancer cells in a mammal using Paramyxovirus as an imaging agent and as an indicator of cancer cell growth in the mammal. The invention further provides genetically engineered Paramyxoviruses, and kits containing the viral compositions disclosed by the invention.

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