Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from hypericum
Reexamination Certificate
2007-04-17
2007-04-17
Lilling, Herbert J. (Department: 1657)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from hypericum
Reexamination Certificate
active
10108235
ABSTRACT:
A method for inhibiting the formation or persistence of brain amyloid deposits in a patient, including administering to the patient a therapeutically effective amount of plant matter from a plant of the genusHypericum, speciesperforatum.
REFERENCES:
patent: 6322824 (2001-11-01), Chatterjee et al.
patent: WO 99/40905 (1999-08-01), None
Puchitler et al. “On the Binding of Congo Red by Amyloid,” pp. 355-364, Sep. 1961. (vol. No. not available.).
Benson et al. “Serum Amyloid a Protein in Amyloidosis, Rheumatic, and Neoplastic Diseases,” Arthritis and Rheumatism, vol. 22, No. 1, pp. 36-42, Jan. 1979.
Kamei et al. “Amyloidosis Associated with Juvenile Rheumatoid Arthritis,” Acta Pathol. Japan. vol. 32 (1), pp. 123-133, 1982.
McDam et al. “Association of Amyloidosis with Erythema Nodosum Leprosum Reactions and Recurrent Neutrophil Leucocytosis in Leprosy,” The Lancet, pp. 572-575, Sep. 1975. (vol. No. not available.).
Metaxas et al. “Familial Mediterranean Fever and Amyloidosis,” Kidney International, vol. 20, pp. 676-685, 1981.
Harada et al. “Human Amyloid Protain: Chemical Variability and Homogeneity,” The Journal of Histochemistry and Cytochemistry, vol. 19, No. 1 pp. 1-15, Jun. 1971.
Johnson et al. “Islet Amyloid, Islet-Amyloid polypeptide, and Diabetes Mellitus,” The New England Journal of Medicine. vol. 321, No. 8 pp. 513-518, Aug. 1989.
Johnson et al. “Islet Amyloid Polypeptide: Mechanisms of Amyloidogenesis in the Pancreatic Islets and Potential Roles in Diabetes Mellitus,” Laboratory Investigation, vol. 66, No. 5, pp. 522-534, 1992.
Gejyo et al. “A New Form of Amyloid Protein Associated with Chronic Hemodialysis was Identified as β2-Microglobulin,” Biochemical and Biophysical Research Communications, vol. 129 No. 3, pp. 701-706, Jun. 1985.
Gejyo et al. “β2—Microglobulin: A New Form of Amyloid Protein Associated with Chronic Hemodialysis,” Kidney International, vol. 30, pp. 385-389, 1986.
Skinner et al. “The Prealbumin Nature of the Amyloid Protein in Familial Amyloid Polyneuropathy (FAP)-Swedish Variety,” Biochemical and Biophysical Research Communications, vol. 99. No. 4, pp. 1326-1332, Apr. 1981.
Joao et al. “Studies on Plasma Transthyretin (prealbumin) in Familial Amyloidotic Polyneuropathy Portuguese Type,” Journal of Laboratory Clinic Medicine, vol. 102, No. 4, pp. 590-603, Oct. 1983.
Joso et al. “Amyloid Fibril Protein in Familial Amyloidotic Polyneuropathy, Portugese Type,” Journal of Clinical Investigation, vol. 74, pp. 104-109, Jul. 1984.
Tawara et al. “Amyloid Fibril Protein in Type I Familial Amyloidotic Polyneuropathy in Japanese,” Journal of Laboratory Clinical Medicine, vol. 98. No. 6, pp. 811-822, Dec. 1981.
Cutler et al. “Tacrine in Alzheimer's Disease,” The New England Journal of Medicine, vol. 328. No. 11, pp. 808-810, Mar. 1992.
Barner et al. “Donepezil Use in Alzheimer Disease,” The Annals of Pharmacotherapy, vol. 32. pp. 70-77, Jan. 1998.
Flood et al. “Amnestic Effects in Mice of Four Synthetic Peptides Homologous to Amyloid β Protein from Patients with Alzheimer Disease,” Procedure of National Academy of Science. vol. 88. pp. 3363-3366. Apr. 1991.
Flood et al. “An Amyloid β-protein Fragment, Aβ[12-28], Equipotently Impairs Post-Training Memory Processing when Injected into Different Limbic System Structures,” Brain Research vol. 663. pp. 271-276. 1994.
Broeckhoven et al. “Amyloid β Protein Precursor Gene and Hereditary Cerebral Hemorrhage with Amyloidosis (Dutch),” Science, vol. 248. pp. 1120-1122, no date of publication is available.
Murrell et al. “A Mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease,” Reports, Oct. 1991.
Haass et al. “The Swedish Mutation Causes Early-onset Alzheimer's Disease by β-secretase Cleavage Within the Secretory Pathway,” Nature Medicine, vol. 1, pp. 1291-1296. No. 12 Dec. 1995.
Hardy et al. “Framing β-amyloid,” Nature Genetics, vol. 1, pp. 233-234. Jul. 1992.
Wagner et al. “Inhibition of MAO by Fractions and Constituents of Hypericum Extract,” Journal of Geriatric Psychiatry and Neurology, vol. 7 Suppl. 1. pp. S57-S59. Oct. 1994.
Thiede et al. “Inhibition of MAO and COMT by Hypericum Extracts and Hypericin,” Journal of Geriatric Psychiatry and Neurology, vol. 7, Suppl. 1 pp. S54-S56. Oct. 1994.
Kerb et al. “Single-Dose and Steady-State Pharmacokinetics of Hypericin and Pseudohypercin,” Antimicrobal Agents and Chemotherapy vol. 40. No. 9 pp. 2087-2093. Sep. 1996.
Lavie et al. “Hypericin as an Inactivator of Infectious Viruses in Blood Components,” Transfusion vol. 35 No. 5 pp. 392-400 1995.
Schulz et al. “Effects of Hypericum Extract on the Sleep EEG in Older Volunteers,” Journal of Geriatric Psychiatry and Neurology vol. 7 Suppl.1 pp. S39-S43. Oct. 1994.
Holden et al. “Treating AIDS With Warts,” Science, vol. 254, pp. 522, no date of publication is available.
Vanderwerf et al. “Hypericin: A New Laser Phototargeting Agent for Human Cancer Cells,” Laryngoscope vol. 106 pp. 479-483. Apr. 1996.
Naiki et al. “Kinetic Analysis of Amyloid Fibril Polymerization In Vitro” Laboratory Investigator vol. 65, No. 1, pp. 104-110, 1991.
Levine et al. “Thioflavine T Interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution”, Protein Science, vol. 2, pp. 404-410, 1993.
Levine et al. “Thioflavine T Interaction with Amyloid β-sheet Structures”, International Journal Experimental Clinical Investigation, vol. 2, pp. 1-6. 1995.
Naiki et al. “First-Order Kinetic Model of Alzheimer's β-Amyloid Fibril Extension In Vitro,” Laboratory Investigation, vol. 74, No. 2, pp. 374-383, Feb. 1996.
Snow et al. “Proteoglycans in the Pathogenesis of Alzheimer's Disease and Other Amyloidoses,” Neurobiology of Aging, vol. 10, pp. 481-497. Apr. 1989.
Castillo et al. “Perlecan Binds to the β-Amyloid Proteins (Aβ) of Alzheimer's Disease, Accelerates Aβ Fibril Formation, and Maintains Aβ Fibril Stability,” Journal of Neurochemistry vol. 69 pp. 2452-2465. 1997.
Glenner et al. “Alzheimer's Disease: Initial Report of the Purification and Characterization of a Novel Cerebrovascular Amyloid Protein,” Biochemical and Biophysical Research Communications, vol. 120. No. 3 pp. 885-890, May 1984.
Colin et al. “Amyloid Plaque Core Protein in Alzheimer Disease and Down Syndrome,” Medical Sciences, vol. 82, pp. 4245-4249, Jun. 1985.
WHO-IUIS Nomenclture Sub-Committee “Nomenclature of Amyloid and Amyloidosis,” Bulletin of the World Health Organization, vol. 71 (1), pp. 105-108, 1993.
Tanzi et al. “Protease Inhibitor Domain Encoded by an Amyloid Protein Precursor mRNA Associated with Alzheimer's Disease,” Nature, vol. 331. pp. 528-532, 1988.
Kitaguchi et al. “Novel Precursor of Alzheimer's Disease Amyloid Protein Shows Protease Inhibitory Activity,” Nature, vol. 331, pp. 530-532, Feb. 1988.
Ponte et al. “A New A4 Amyloid mRNA Contains a Domain Homologous to Serine Proteinase Inhibitors,” Nature, vol. 331. pp. 525-527, no date of publication is available.
Grundke-Iqbal et al. “Abnormal Phosphorylation of the Microtubule-Associated Protein t (Tau) in Alzheimer Cytoskeletal Pathology,” Procedure of National Academy of Science, vol. 83. pp. 4913-4917, 1986.
Kosik et al. “Microtubule-associated Protein Tau (t) is a major antigenic component of paired helical filaments in Alzheimer disease,” Procedure of Natural Academy of Science, vol. 83. pp. 4044-4048, Jun. 1986.
Lee et al. “A68: A Major Subunit of Paire
Castillo Gerardo
Snow Alan D.
Dwyer Patrick M
Lilling Herbert J.
ProteoTech, Inc.
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