Methods of synthesizing N -hydroxysuccinimidyl carbonates

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C560S115000

Reexamination Certificate

active

07989641

ABSTRACT:
The present disclosure relates to methods of synthesizing N-hydroxysuccinimidyl-carbonate intermediates from the corresponding sulfones useful in the preparation of 1-(acyloxy)-alkyl carbamate prodrugs.

REFERENCES:
patent: 4126684 (1978-11-01), Robson et al.
patent: 4760057 (1988-07-01), Alexander
patent: 4916230 (1990-04-01), Alexander
patent: 5006560 (1991-04-01), Kreutner et al.
patent: 5684018 (1997-11-01), Alexander
patent: 5719185 (1998-02-01), Bountra et al.
patent: 6117908 (2000-09-01), Andrews et al.
patent: 6818787 (2004-11-01), Gallop et al.
patent: 6833140 (2004-12-01), Cundy et al.
patent: 6927036 (2005-08-01), Gallop et al.
patent: 6972341 (2005-12-01), Gallop et al.
patent: 7109239 (2006-09-01), Gallop et al.
patent: 7186855 (2007-03-01), Gallop et al.
patent: 7227028 (2007-06-01), Gallop et al.
patent: 7232924 (2007-06-01), Raillard et al.
patent: 7300956 (2007-11-01), Gallop et al.
patent: 7351740 (2008-04-01), Zerangue et al.
patent: 2005/0070715 (2005-03-01), Bhat et al.
patent: 2005/0154057 (2005-07-01), Estrada et al.
patent: 2008/0161393 (2008-07-01), Barrett et al.
patent: 2009/0118365 (2009-05-01), Benson et al.
patent: 2009/0192222 (2009-07-01), Yao et al.
patent: 2009/0192325 (2009-07-01), Gallop et al.
patent: 2009/0215809 (2009-08-01), Yao et al.
patent: WO 01/05813 (2001-01-01), None
patent: WO 01/08675 (2001-02-01), None
patent: WO 01/26638 (2001-04-01), None
patent: WO 02/096404 (2002-12-01), None
patent: WO 02/100347 (2002-12-01), None
patent: WO 2004/089289 (2004-10-01), None
patent: WO 2005/010011 (2005-02-01), None
patent: WO 2005/027850 (2005-03-01), None
patent: WO 2005/066122 (2005-07-01), None
patent: WO 2008/077241 (2008-07-01), None
Sun, Xicheng. Synthesis and Evaluation of Novel Pseudomycin Side-Chain Analogues, Part 3. Bioorganic and Medicinal Chemistry Letters. 11 (2001) 3055-3059.
Kouge et al., Peptide synthesis in aqueous solution. I. Application ofp-dialkyl-sulfoniophenols as a water-soluble coupling reagent,Bull. Chem. Soc. Jpn. (1987), 60: 2409-2418.
International Search Report, dated Jan. 4, 2010, issued in corresponding PCT application No. PCT/US2009/053188 (5 pages).
Written Opinion of the International Searching Authority, dated Jan. 4, 2010, issued in corresponding PCT application No. PCT/US2009/053188 (5 pages).
U.S. Appl. No. 61/087,056, filed Aug. 7, 2008, Raillard et al.
Ciccaglione et al., Effect of acute and chronic administration of the GABABagonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease.Gut(2003), 52, 464-470.
Van Herwaarden et al., The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease.Aliment. Pharmacol. Ther. (2002), 16, 1655-1662.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of synthesizing N -hydroxysuccinimidyl carbonates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of synthesizing N -hydroxysuccinimidyl carbonates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of synthesizing N -hydroxysuccinimidyl carbonates will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2676591

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.