Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1988-10-31
1993-08-17
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544361, 546 77, 540108, C07J 7500, C07J 7300
Patent
active
052370615
ABSTRACT:
A process for preparing compounds of the formula ##STR1## which comprises reacting an imidazolide of the formula ##STR2## with an amine of the formula NHR.sub.4 R.sub.5 in the presence of a Grignard reagent to form a compound of formula I or reacting an imidazolide of formula II with a compound of the formula R.sub.6 Mgx to form a compound of formula I.
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Amato Joseph S.
Bhattacharya Apurba
Dolling Ulf H.
Williams John M.
Caruso Charles M.
Merck & Co. , Inc.
Shah Mukund J.
Ward E. C.
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