Methods of synthesis of peptidyl argininals

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

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530324, 530325, 530326, 530327, 530328, 530329, 530330, 530345, 546221, 546243, C07K 500, C07K 700, C07K 1700, C07D21122

Patent

active

055147771

ABSTRACT:
This invention provides solution-phase methods for the synthesis of peptidyl argininals and to novel reagents useful therein.

REFERENCES:
patent: 4316889 (1982-02-01), Bajusz et al.
patent: 4703036 (1987-10-01), Bajusz et al.
patent: 5153176 (1992-10-01), Abe et al.
Bajusz, Sandor, et al., J. Med. Chem., 1990, 33, pp. 1739-1735.
McConnell, Rose, et al., J. Med. Chem., 1990, 36, pp. 1084-1089.
Shuman, Robert T., et al., J. Med. Chem., 1993, 36, pp. 314-319.

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