Methods of surface modification of a flexible substrate to...

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Reexamination Certificate

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C428S448000, C427S002100, C427S002110, C427S002310, C427S289000

Reexamination Certificate

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10660760

ABSTRACT:
The present invention provides methods of producing a surface with enhanced cell-adhesive properties comprising applying a stress to a polymeric matrix. The strained matrix is then modified by grafting a self-assembled monolayer onto the strained matrix, with the self-assembled monolayer comprising at least one exposed functional group. At least one cell-adhesive molecule can then be coupled to the at least one exposed functional group on the self-assembled monolayer to produce a surface with enhanced cell-adhesive properties.

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