Methods of stimulating the immune system

Details Methods of stimulating the immune system Methods of stimulating the immune system

2005-01-18

2005-01-18

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

C424S195180, C514S675000, C514S691000, C514S729000, C514S738000

Reexamination Certificate

active

06844013

ABSTRACT:
This invention relates to a compound or group of compounds present in an active principle derived from plants of speciesEuphorbia peplus, Euphorbia hirtaandEuphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II.

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