Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-04-26
2005-04-26
Eyler, Yvonne (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120, C435S007200, C530S387100, C536S023500
Reexamination Certificate
active
06884590
ABSTRACT:
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.
REFERENCES:
patent: 3654090 (1972-04-01), Schuurs
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 4016043 (1977-04-01), Schuurrs et al.
patent: 4698195 (1987-10-01), Okumura et al.
patent: 4699880 (1987-10-01), Goldstein
patent: 4704692 (1987-11-01), Ladner
patent: 4800159 (1989-01-01), Mullis et al.
patent: 4935234 (1990-06-01), Todd et al.
patent: 5002873 (1991-03-01), St. John et al.
patent: 5085318 (1992-02-01), Leverick
patent: 5091302 (1992-02-01), Newman et al.
patent: 5114842 (1992-05-01), Plow et al.
patent: 5137806 (1992-08-01), Lemaistre et al.
patent: 5147637 (1992-09-01), Wright et al.
patent: 5219997 (1993-06-01), Schlossman et al.
patent: 5227369 (1993-07-01), Rosen et al.
patent: 5234810 (1993-08-01), Kehrli, Jr. et al.
patent: 5235049 (1993-08-01), McClelland et al.
patent: 5236081 (1993-08-01), Fitzsimmons et al.
patent: 5264554 (1993-11-01), Newman
patent: 5272263 (1993-12-01), Hession et al.
patent: 5284931 (1994-02-01), Springer et al.
patent: 5518488 (1996-05-01), Schluger
patent: 5590769 (1997-01-01), Lin
patent: 5947281 (1999-09-01), Kaneff
patent: 9116928 (1991-04-01), None
patent: 9202819 (1991-07-01), None
patent: 9222323 (1992-06-01), None
patent: 9312248 (1992-12-01), None
patent: 9404188 (1993-08-01), None
Stratagene Catalog, 1988, p. 39.*
Paul, ed. Fundamental Immunology 4th edition 1998 pp. 663-665.*
Ausubel, F. M. et al., eds., “Current Protocols in Molecular Biology,” Wiley Intersciences, New York, (1987, 1989).
Ballantyne, C., et al., “Short Communication, Assignment of the Gene for Intercellular Adhesion Molecule-1 (Icam-1) to Proximal Mouse Chromosome 9,”Genomics —9:547-550 (1991).
Benoit, R., et al., “Presence of somatostatin-28-(1-12) in hypothalamus and pancreas,”Proc. Natl. Acad. Sci. USA—79:917-921 (1982).
Brambs et al., “Inflammatory Bowel Disease: Radiographical Diagnostics.” (Reprints available at the Department of Radiography, Albert Ludwigs University Hospital, Freiburg, Federal Republic of Germany),. pp. 3-62 (Undated).
Burks, C., et al., “GenBank,”Nucleic Acids Res.(Suppl.)—20:2065-2069 (1992).
Cardullo, R.A., et al., “Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer,”Proc. Natl. Acad. Sci. USA—85:8790-94 (1988).
Diamond, M.S., et al., “Binding of the Integrin Mac-1 (CD11b/CD18) to the Third Immunoglobulin-like Domain of ICAM-1 (CD54) and its Regulation by Glycosylation,”Cell—65(6):961-971 (1991).
Fawcett, J., et al., “Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukycytes,”Nature—360:481-84 (1992).
Hogg, N. and Landis, R., “Adhesion molecules in cell interactions,”Curr. Opin. Immunol.—5:383-390 (1993).
Kita, Y., et al., “Sequence and expression of rat ICAM-1,”Biochim. Biophys. Acta—1131:108-111 (1992).
Kuntz, H.D., et al., “Inflammatory Bowel Disease: Endoscopic Diagnostics.” (Reprints available at the Department of Gastroenterology and Hepatology “Bergmannsheil” Hospital, University of Bochum, Federal Republic of Germany), pp. 3-38 (Undated).
Landegren, U., et al., “A Ligase-Mediated Gene Detection Technique,”Science—241:1077-80 (1988).
Lasky, L., “Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation,”Science—258:964-969 (1992).
Lemna, W.K., et al., “Mutation Analysis for Heterozygote Detection and the Prenatal Diagnosis of Cystic Fibrosis,”N. Eng. J. Med.—322:291-296 (1990).
Lipsky, P., “Structure, Function and Regulation of Molecules Involved in Leukocyte Adhesion,” New York: Springer-Verlag (1993) (Book-not being sent).
Lorenz-Meyer, H., “Inflammatory Bowel Disease Laboratory Diagnostics.” (Reprints available from the City Hospital, Friedrichshafen, Federal Republic of Germany), pp. 3-29 (Undated).
Maniatis, T. et al., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, pp. (1982).
McEver, R., “Leukocyte—endothelial cell interactions,”Curr. Opin. Cell. Biol.—4:840-849 (1992).
Nakamura, S., et al., “In situ expression of the cell adhesion molecules in inflammatory bowel disease: Evidence of immunologic activation of vascular endothelial cells,”Lab Invest.—69(1):77-85 (1993).
Saxon, E.Z., et al., “A Distinct Subset of Antineutrophil Cytoplasmic Antibodies is Associated with Inflammatory Bowel Disease,”J. Allergy Clin. Immunol.—86(2):202-210 (1990).
Schoelmerich, J., “Inflammatory Bowel Diseases: Early Symptoms and Differential Diagnosis of Chronic Inflammatory Bowel Diseases,” (Reprints available from the University of Freiburg, Department of Internal Medicine, Hugstetter Straβe 55, D-7800 Freiburg, W. Germany), pp. 2-20.
Shanahan, F., et al., “Inflammatory Bowel Disease,”Textbook of Internal Medicien—81:489-502; (W.N. Kelley et al. (editor), 2ndedition, J. B. Lippincott Company, Philadelphia, PA (1992).
Smith, C., “Transendothelail Migration,” Harlan, J. and Liu, D., eds., W.H. Freeman & Co., New York, pp. 83-115 (1992).
Smith, C., et al., “Adherence of Neutrophils to Canine Cardiac Myocytes In Vitro Is Dependent on Intercellular Adhesion Molecule-1,”J. Clin. Invest.—88:1216-1223 (1991).
Smith, C.W., et al., “Recognition of an Endothelial Determinant for CD18-dependent Human Neutrophil Adherence and Transendothelial Migration,”J. Clin. Invest.—82:1746-1756 (1988).
Springer, T.A., et al., “Leukocyte Adhesion Molecules Structure Function and Regulation,” New York, Springer-Velag (1990) (Book—Table of Contents).
Springer, T.A., et al., “Adhesion receptors of the immune system,”Nature—346:425-433 (1990).
Staunton D.E., et al., “Primary Structure of ICAM-1 Demonstrates Interaction Between Members of the Immunoglobulin and Integrin Supergene Families,”Cell—52:925-933 (1988).
Stites, D. P., et al., Chapter 22 of the 4thedition ofBasic and Clinical Immunology, Lange Medical Publications, Los Altos, California (1982).
Tomassini, J.E., et al., “cDNA Cloning Reveals That The Major Group Rhinovirus Receptor on HeLa Cells is Intercellular Adhesion Molecule 1, ”Proc. Natl. Acad. Sci. USA—86:4907-4911 (1989).
Voraberger, G., et al., “Cloning of the Human Gene For Intercellular Adhesion Molecule 1 and Analysis of Its 5'-Regulatory Region,”The Journal of Immunology—147:(8):2777-2786 (1991).
Weber, J. and May, P., “Abundant Class of Human DNA Polymorphisms Which Can Be Typed Using the Polymerase Chain Reaction,”Am. J. Hum. Genet.—44:388-396 (1989).
Yang, H. et al., “Association of intercellular adhesion-molecule-1 (ICAM-1) gene with subsets of Inflammatory bowel disease (BID) stratified by anti neutrohil cytoplasmic antibodies (ANCAs),”Clinical Research—42(1):76A (1994).
Yang, H., et al., “Genetic Heterogeneity Within UC and Crohn's Defined by Antineutrophil Cytoplasmic Antibodies (ANCAs) and Intercellular Adhesion Molecule-1 (ICAM-1) Polymorphisms,”Gastroenterology 106(4) Part 2 (A794-AGA Abstracts).
Beaudet Arthur L.
Rotter Jerome I.
Targan Stephan R.
Vora Devendra
Yang Huiying
Cedars-Sinai Medical Center
Eyler Yvonne
McDermott & Will & Emery
Murphy Joseph S.
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