Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2002-05-08
2008-11-18
Wessendorf, T. D. (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120, C435S004000, C435S091500, C435S091500
Reexamination Certificate
active
07452675
ABSTRACT:
The invention relates, in part, to methods useful in identifying molecules, that bind TRPM4b, which modulate TRPM4bion channel activity, and/or which alter expression of TRPM4bwithin cells. The TRPM4bchannels as described herein contain TRPM4bpolypeptides, which are in turn encoded by TRPM4bnucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM4bpolypeptides, which exhibit one or more of the unique TRPM4bproperties described herein.
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Fleig Andrea
Penner Reinhold
Morgan Lweis & Bockius LLP
Talukder Gargi
The Queen's Medical Center
Trecartin Richard F.
Wessendorf T. D.
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