Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2006-05-09
2006-05-09
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S025000, C435S325000, C435S361000
Reexamination Certificate
active
07041501
ABSTRACT:
The present invention relates to methods of screening drug candidates for toxic effects on human cells. The invention provides methods for determining idiosyncratic toxicity of test compounds.
REFERENCES:
patent: 5164313 (1992-11-01), Gelboin et al.
patent: 5342777 (1994-08-01), Cole et al.
patent: 5356806 (1994-10-01), Harris et al.
patent: 5506131 (1996-04-01), Harris et al.
patent: 5529920 (1996-06-01), Cole et al.
patent: 5614505 (1997-03-01), Gmeiner et al.
patent: 5660986 (1997-08-01), Harris et al.
patent: 5665589 (1997-09-01), Harris et al.
patent: 5759782 (1998-06-01), Pastan et al.
patent: 5869243 (1999-02-01), Jauregui et al.
patent: 6214803 (2001-04-01), Kuo et al.
patent: 6852845 (2005-02-01), Rothberg et al.
patent: 2004/0010809 (2004-01-01), Wolf et al.
Pfeifer A.M. et al., Proc. Natl.Acad.Sci., USA, vol. 90, pp. 5123-5127 (1993).
Evans, W.E. and Relling M.V., Science, vol. 286 (5439), pp. 487-491 (1999).
Schiller et al., Toxicology in Vitro, vol. 6 No. 6, pp. 575-578 (1992).
Leeder et al., Drug Metabolite Toxicity Assessed in Human Lymphocytes With a Purified, Reconstituted Cytochrome P-450 System1, Feb. 22, 1988, pp. 956-962.
Durham Stephen K.
Flint Oliver P.
Moulin Frederic
Bergen Briana C.
Bristol--Myers Squibb Company
Carey Brian C.
Lankford , Jr. Leon B.
LandOfFree
Methods of screening for toxicity of test compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of screening for toxicity of test compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of screening for toxicity of test compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3533928