Methods of screening for modulators of respiratory syncytial vir

Details Methods of screening for modulators of respiratory syncytial vir Methods of screening for modulators of respiratory syncytial vir

1997-12-19

2000-01-25

Wortman, Donna

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 72, 435 79, C12Q 170

Patent

active

060176946

ABSTRACT:
Methods of screening for modulators of respiratory syncytial virus matrix protein interaction are described. A host cell carrying a nucleic acid sequence encoding RSV matrix protein or fragments of RSV matrix protein which can bind to RSV matrix protein is cultured and the RSV matrix protein or RSV fragments are expressed. The interaction of the expressed RSV matrix protein or fragments is measured. A test sample is then added to the expressed RSV matrix protein or fragments and the effect of the test sample on RSV matrix protein interaction is measured.

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