Methods of screening for compounds that interact with human P.su

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 72, 435 691, 435325, 435348, 530350, 536 235, C12Q 100, C07K 14705, C12N 1512

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active

060635827

ABSTRACT:
A novel subtype of the P.sub.2 -purinergic receptor, referred to as the P.sub.2U2 receptor, is disclosed. This receptor is activated by four of its agonists in the following order of specificity: UTP>UDP>ADP>ATP. Nucleic acids encoding the receptor and associated screening and therapeutic methods also are disclosed.

REFERENCES:
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