Methods of screening for B cell activity modulators

Details Methods of screening for B cell activity modulators Methods of screening for B cell activity modulators

2005-07-05

2005-07-05

Ponnaluri, Padmashri (Department: 1639)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S091100, C435S091500, C435S091500, C435S091500, C435S091500, C436S518000, C536S023100, C536S023200

Reexamination Certificate

active

06913882

ABSTRACT:
The invention provides for the identification of all genes, whether known or novel, which are differentially expressed within and among B cells, making possible the characterization of their temporal regulation and function in the B cell response and/or in B cell mediated disorders. Expression profiles, nucleic acids and proteins are provided for differing states of B cells, including resting, naive, activated, tolerant and immunosuppressed B cells. The present invention makes possible the identification and characterization of targets useful in prognosis, diagnosis, monitoring, rational drug design, and/or therapeutic intervention of immune system disorders.

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