Methods of screening for agents that delay a cell cycle and comp

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 6, 435 71, 435 721, 435 32, 536 231, 536 232, C12Q 168, G01N 3353

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061329541

ABSTRACT:
The present invention provides for methods of screening for agents which delay the cell cycle and methods of delaying the cell cycle. Analogues of Era having arginine, histidine, or lysine at amino acid codon 17 are embodied by the present invention. Human and other homologs of bacterial Era amino acid and nucleic acid sequences are provided in the present invention. Vectors, host cells, protein preparations, cell cultures, and compositions comprising said analogue are also set forth in the present invention.

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