Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition
Reexamination Certificate
2007-01-23
2007-01-23
Swartz, Rodney P (Department: 1645)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Testing efficacy or toxicity of a compound or composition
C424S009100, C424S114000, C424S093470, C424S260100, C435S874000, C536S016800
Reexamination Certificate
active
08962750
ABSTRACT:
Screening procedures are disclosed for identifying compounds useful for inhibiting infection or pathogenicity. Methods are also disclosed for identifying pathogenic virulence factors.
REFERENCES:
patent: 4713378 (1987-12-01), Perrone et al.
patent: 5270448 (1993-12-01), Payne
patent: 5366995 (1994-11-01), Savage et al.
patent: WO 94/16077 (1994-07-01), None
patent: WO 95/11969 (1995-05-01), None
Conrad et al, “Efficacy of aztreonam in the treatment of skieletal infections due toPseudomonas aeruginosa”, Reviews of Infectious Diseases, vol. 13, supplement 7, pp. S634-S639, Jun. 1, 1991.
Webster's II, New Riverside University Dictionary, The Riverside Publishing Company, Jan. 1, 1988, pp. 512 and 778.
Geels, F.P. “Pseudomonas tolaasiicontrol by kasugamycin in cultivated mushrooms (Agaricus bisporus)”,J. Applied Bacteriology79: 38-42, (1995).
Grewal P.S. and Hand, P. “Effects of bacteria isolated from a saprophagous rhabditid nematodeCaenorhabditis eleganson the mycelial growth ofAgaricus bisporus”, J. Applied Bacteriology, 72: 173-179, (1992).
Alexander et al., “Surgical Infections and Choice of Antibiotics,” In: Textbook of Surgery, Sabiston, D.C., (ed.), Saunders, W.B., Philadelphia, PA pp. 221-236 (1991).
Bent et al., “RPS2 ofArabidopsis thaliana: A Leucine-Rich Repeat Class of Plant Disease Resistance Genes,” Science 265:1856-1860 (1994).
Berka et al., “Phospholipase C (Heat-Labile Hemolysin) ofPseudomonas aeruginosa: Purification and Preliminary Characterization,” J. Bacteriology 152:239-245 (1982).
Bestwick et al., “Localization of Hydrogen Peroxide Accumulation During the Hypersensitive Reaction of Lettuce Cells toPseudomonas syringaepvphaseolicola,” The Plant Cell 9:209-221 (1997).
Bucher, G. E., “Pathogens of Tobacco and Tomato Hornworms,” Journal of Invertebrate Pathology 9:82-89 (1967).
Bulla, Lee A. Jr., “Bacteria as Insect Pathogens,” Annu. Rev. Microb. 29:163-190 (1975).
Chadwick, June Stephens, “Serological Responses of Insects,” Federation Proceedings 26:1675-1679 (1967).
Chadwick et al., “Adherence Patterns and Virulence forGalleria melonellaLarvae of Isolates ofSerratia marcescens,” Journal of Invertebrate Pathology 55:133-134 (1990).
Charpentier et al., “The Bacterial Flora of the Midgut of Two Danish Populations of Healthy Fifth Instar Larvae of the Turnip Moth,Scotia segetum,” Journal of Invertebrate Pathology 32:59-63 (1978).
Cho et al., “Ornamental Plants as Carriers ofPseudomonas aeruginosa,” Phytopathology 65:425-431 (1975).
Debener et al., “Identification and Molecular Mapping of a SingleArabidopsis thalianaLocus Determining Resistance to a PhytopathogenicPseudomonas syringaeIsolate,” The Plant Journal 1:289-302 (1991).
Dong et al., “Induction ofArabidopsisDefense Genes by Virulent and AvirulentPseudomonas syringaeStrains and by a Cloned Avirulence Gene,” The Plant Cell 3:61-72 (1991).
Dunphy, Gary B., “Interaction of Mutants ofXenorhabdus nematophilus(Enterobacteriaceae) With Antibacterial Systems ofGalleria mellonellaLarvae (Insecta: Pyralidae),” J. Insect Physiol. 40:161-168 (1994).
Dunphy et al., “Octopamine, a Modulator of the Haemocytic Nodulation Response of Non-immuneGalleria mellonellaLarvae,” J. Insect Physiol. 40:267-272 (1994).
Elrod et al., “Pseudomonas aeruginosa; Its Role as a Plant Pathogen,” J. Bacteriology 46:633-645 (1942).
Elrod et al., “A Phytopathogenic Bacterium Fatal to Laboratory Animals,” Science 94:520-521 (1941).
Fenselau et al., “Determinants of Pathogenicity inXanthomonas campestrispv.vesicatoriaare Related to Proteins Involved in Secretion in Bacterial Pathogens of Animals,” Molecular Plant-Microbe Interactions 5:390-396 (1992).
Fuqua et al., “Quorum Sensing in Bacteria: the LuxR-LuxI Family of Cell Density-Responsive Transcriptional Regulators,” J. Bacteriology 176:269-275 (1994).
Gingrich, Richard E., “Acquired Humoral Immune Response of the Large Milkweed Bug,Oncopeltus fasciatus(Dallas), to Injected Materials,” J. Ins. Physiol. 10:179-194 (1964).
Green et al., “Agricultural Plants and Soil as a Reservoir forPseudomonas aeruginosa”, Appl. Microbiology 28:987-991 (1974).
Gough et al., “hrp Genes ofPseudomonas solanacearumare Homologous to Pathogenicity Determinants of Animal Pathogenic Bacteria and are Conserved Among Plant Pathogenic Bacteria,” Molecular Plant-Microbe Interactions 5:384-389 (1992).
Harshey et al., “Spinning tails: homologies among bacterial flagellar systems,” Trends in Microbiology 4:226-231 (1996).
Holloway, “Genetic Recombination inPseudomonas aeruginosa,” J. Gen. Microbiol. 13:572-581 (1955).
Hoffman et al., “Insect Immunity:Galleria mellonellaand Other Lepidoptera Have Cecropia-P9-Like Factors Active Against Gram Negative Bacteria,” Insect Biochem. 11:537-548 (1981).
Huang et al., “ThePseudomonas syringaepv.syringae61 hrpH Product, an Envelope Protein Required for Elicitation of the Hypersensitive Response in Plants,” J. Bacteriology 174:6878-6885 (1992).
Huang et al., “Characterization of thePseudomonas syringaepv.syringae61 hrpJ and hrpI Genes: Homology of Hrpl to a Superfamily of Proteins Associated with Protein Translocation,” Molecular Plant-Microbe Interactions 6:515-520 (1993).
Iglewski et al., “NAD-Dependent Inhibition of Protein Synthesis byPseudomonas aeruginosaToxin,” Proc. Nat. Acad. Sci. USA 72:2284-2288 (1975).
Ishimoto et al., “Formation of Pilin inPseudomonas aeruginosaRequires the Alternative σ Factor (RpoN) of RNA polymerase,” Proc. Natl. Acad. Sci. USA 86:1954-1957 (1989).
Jarosz, J., “Interaction ofPseudomonas aeruginosaProteinase with the Inducible Non-Self Response System of Insects,” Cytobios 83:71-84 (1985).
Johnston et al., “Transcriptional activation ofSalmonella typhimuriumInvasion Genes by a Member of the Phosphorylated Response-Regulator Superfamily,” Mol. Microbiol. 22:715-727 (1996).
Kamon et al., “Immune Response of Locusts to Venom of the Scorpion”, Journal of Invertebrate Pathology, 7:192-198 (1965).
Kaska, Milan, “The Toxicity of Extracellular Proteases of the BacteriumSerratia marcescensfor Larvae of Greater Wax Moth,Galleria mellonella,” Journal of Invertebrate Pathology 27:271 (1976).
Kanost et al., “Isolation and Characterization of a Hemocyte Aggregation Inhibitor From Hemolymph ofManduca sextaLarva,” Archives of Insect Biochemistry and Physiology 27:123-136 (1994).
Kominos et al., “Introduction ofPseudomonas aeruginosainto a Hospital via Vegetables,” Appl. Microbiol. 24:567-570 (1972).
Kovalchik et al., “Neisseria gonorrhoeae: Colonial Morphology of Rectal Isolates,” Appl. Microbiol. 23:986-989 (1972).
Kunkel et al., “RPS2, an Arabidopsis Disease Resistance Locus Specifying Recognition ofPseudomonas syringaeStrains Expressing the Avirulence Gene avrRpt2,” The Plant Cell 5:865-875 (1993).
Laville et al., “Global control inPseudomonas fluorescensMediating Antibiotic Synthesis and Suppression of Black Root Rot of Tobacco,” Proc. Natl. Acad. Sci. USA 1562-1566 (1992).
Lee et al., “Type III Secretion Systems: Machines to Deliver Bacterial Proteins into Eukaryotic Cells?,” Trends in Microbiol. 5:148-156 (1997).
Lemaitre et al., “The Dorsoventral Regulatory Gene Cassete spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults,” Cell 86:973-983 (1996).
Lysenko, O., “Pseudomonas-An Attempt at a General Classification,” J. Gen. Microbiol. 25:379-408 (1963).
Lysenko, O., “The Mechanisms of Pathogenicity ofPseudomonas aeruginosa(Schroeter) Migula, I. The Pathogenicity of Strain N-06 for Larvae of the Greater Wax Moth,Galleria mellonella(L
Ausubel Frederick M.
Broeks Annegien
Heard Jacqueline
Jander Georg
Mahajan-Miklos Shalina
Clark & Elbing LLP
Swartz Rodney P
The General Hospital Corporation
The Netherlands Cancer Institute
LandOfFree
Methods of screening compounds useful for prevention of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of screening compounds useful for prevention of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of screening compounds useful for prevention of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3762547