Methods of production and use of liquid formulations of plasma p

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530383, 530384, 530829, 530830, 514 21, A61K 3514

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active

059257385

ABSTRACT:
The present invention relates to the preparation and use of liquid formulations of plasma proteins, particularly blood coagulation factors. More specifically, the present invention relates to stable liquid formulations of Factor VIII and Factor IX that can be administered by injection or infusion to provide a constant level of the coagulation factor in the blood.

REFERENCES:
patent: 3560475 (1971-02-01), Fekete et al.
patent: 4447416 (1984-05-01), Memadre-Aronson et al.
patent: 5055557 (1991-10-01), Zimmermann
patent: 5110907 (1992-05-01), Kosow et al.
patent: 5259951 (1993-11-01), Arrigli et al.
patent: 5288853 (1994-02-01), Bhattacharva et al.
patent: 5639857 (1997-06-01), Zimmermann

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