Methods of producing polyketide synthase mutants and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

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C702S027000

Reexamination Certificate

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10450230

ABSTRACT:
The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acids encoding such non-native polyketide synthases. Also disclosed are methods of producing mutant polyketide synthases, and methods of altering the activity and/or substrate specificity of putative polyketide synthases.

REFERENCES:
patent: 6390821 (2002-05-01), Shokat
patent: WO 01/07579 (2001-02-01), None
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