Methods of producing influenza vaccine compositions

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

Reexamination Certificate

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C424S204100, C424S205100, C424S209100

Reexamination Certificate

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10788236

ABSTRACT:
Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided.

REFERENCES:
patent: 4000257 (1976-12-01), Cano
patent: 4338296 (1982-07-01), Lobmann et al.
patent: 4500512 (1985-02-01), Barme
patent: 4512285 (1985-04-01), McGehee
patent: 6039958 (2000-03-01), Koyama et al.
patent: WO 03/091401 (2003-11-01), None
Arora et. al., Concentration and Purification of Influenza Virus from Allantoic Fluid,Analytical Biochemistry, (1985) 144:189-192.
Cha et al., Genotypic Stability of Cold-Adapted Influenza Virus Vaccine in an Efficacy Clinical Trial,J. Clin. Micro., (2000) 38(2):839-845.
Belshe et al., The Efficacy of Live Attenuated, Cold-Adapted, Trivalent, Intranasal Influenza Virus Vaccine in Children,N. Engl. J. Med., (1998) 338:1405-12.
Boyce et al., Safety and Immunogenicity of Adjuvanted and Unadjuvanted Subunit Influenza Vaccines Administered Intranasally to Healthy Adults,Vaccine, (2001) 19:217-26.
Denizot et al., Rapid Colorimetric Assay for Cell Growth and Survival (Modifications to the Tetrazolium Dye Procedure Giving Improved Sensitivity and Reliability),J. Immun. Methods(1986) 89:271-277.
Edwards et al., A Randomized Controlled Trial of Cold-Adapted and Inactivated Vaccines for the Prevention of Influenza A Disease,J. Infect. Dis. (1994) 169:68-76.
Furminger, Vaccine Production,Textbook of Influenzapp. 324-332.
Gerlier et al., Use of MTT Colorimetric Assay to Measure Cell Activation,J. Immuno. Methods, (1986) 94:57-63.
Heeg et al., A Rapid Colorimetric Assay for the Determination of IL-2-Producing Helper T Cell Frequencies,J. Immuno Methods, (1985) 77:237-246.
Maassab, Adaptation and Growth Characteristics of Influenza Virus at 25 degrees C,Nature(1967) 213:612-614.
Maassab et al., Evaluation of a Cold-Recombinant Influenza Virus Vaccine in FerretsJ. Infect. Dis., (1982) 146:780-790.
Merten et al., Production of Influenza Virus in Cell Cultures for Vaccine Preparation,Novel Strategies in Design and Production of Vaccines, (1996) pp. 141-151.
Mosmann, Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assays,J. Immuno. Methods, (1983) 65:55-63.
Murphy & Coelingh, Principles Underlying the Development and Use of Live Attenuated Cold-Adapted Influenza A and B Virus Vaccines,Viral Immunol., (2002) 15:295-323.
Nichol et al., Effectiveness of Live, Attenuated Intranasal Influenza Virus Vaccine in Healthy, Working Adults: A Randomized Controlled Trial,JAMA(1999) 282:137-44.
Reimer, et al., Influenza Virus Purification with the Zonal Ultracentrifuge,Science(1966) 152:1379-1381.
Tada, et al., An Improved Colorimetric Assay for Interleukin 2,J. Immuno. Methods, (1986) 93:157-165.
Virus cultivation, Detection, and Genetics, S. J. Flint, L.W. Enquist, R.M. Krug, V.R. Racaniello and A.M. Skalka, “Principles of Virology,” ASM Press, Washington, p. 27-62, (2000).
Vistica et al., Tetrazolium-Based Assays for Cellular Viability: A Critical Examination of Selected Parameters Affecting Formazan Production,Cancer Research(1991) 51: 2515-2520.
Wareing & Tannock, Preparation and Characterisation of Attenuated Cold-Adapted Influenza A Reassortants derived from the A/Leningrad/134/17/57 donor strain,Vaccine, (2002) 20:2082-2090.

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