Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2011-04-19
2011-04-19
Johnston, Phillip A (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S282000, C250S297000
Reexamination Certificate
active
07928367
ABSTRACT:
A simple and efficient method of preparing a sample in the measurement according to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) capable of inhibiting any ion suppression by impurities, such as inorganic salts and surfactants, contained in the sample. An analyte and matrix molecules are co-crystallized in the presence of porous microparticles. Preferably, this co-crystallization is carried out by bringing the analyte, matrix molecules and porous microparticles into contact with each other on a target plate and thereafter drying the mixture. The porous microparticles consist of an ion exchanger having an average particle diameter of not more than 50 μm, preferably a strongly basic anion exchanger.
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Asanuma Miwako
Fukuzawa Seketsu
Hirota Hiroshi
Yokoyama Shigeyuki
Birch & Stewart Kolasch & Birch, LLP
Johnston Phillip A
Riken
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