Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...
Patent
1997-03-17
1999-10-12
Gitomer, Ralph
Chemistry: molecular biology and microbiology
Maintaining blood or sperm in a physiologically active state...
4351733, 424532, A01N 102
Patent
active
059653493
ABSTRACT:
Methods of photodecontamination are described which employ phosphate buffered aqueous solutions. Blood products comprising plasma are diluted with these solutions and treated with psoralen.
REFERENCES:
patent: Re32874 (1989-02-01), Rock et al.
patent: 4124598 (1978-11-01), Herast et al.
patent: 4157723 (1979-06-01), Granzow et al.
patent: 4169204 (1979-09-01), Hearst et al.
patent: 4196281 (1980-04-01), Hearst et al.
patent: 4265280 (1981-05-01), Ammann et al.
patent: 4390619 (1983-06-01), Harmening-Pittiglio
patent: 4412835 (1983-11-01), Spencer
patent: 4447415 (1984-05-01), Rock et al.
patent: 4695460 (1987-09-01), Holme
patent: 4704352 (1987-11-01), Miripol et al.
patent: 4727027 (1988-02-01), Wiesehahn et al.
patent: 4748120 (1988-05-01), Wiesehahn
patent: 4828976 (1989-05-01), Murphy
patent: 4878891 (1989-11-01), Judy et al.
patent: 4925665 (1990-05-01), Murphy
patent: 4960408 (1990-10-01), Klainer et al.
patent: 4992363 (1991-02-01), Murphy
patent: 5709991 (1998-01-01), Lin et al.
patent: 5712085 (1998-01-01), Wollwitz et al.
Dodd R. Inactivation of Viruses in Platelet Suspensions that Retain Their in vitro Characteristics. Transfusion 31(6)483-490, 1991.
Murphy and Gardner, "Effect of storage temperature on maintenance of platelet viability--deleterious effect on refrigerated storage", New Eng. J. Med. 280:1094-1098 (1969).
B.J. Grossman et al., "Screening blood donors for gastrointestinal illness: a strategy to eliminate carriers of Yersinia enterocolitica," Transfusion 31:500-501 (1991).
B.A. Myhre, "Fatalities from Blood Transfusion," JAMA 244:1333-1335 (1980).
J.M. Heal et al., "Fatal Salmonella septicemia after platelet transfusion," Transfusion 27:1-5 (1987).
D.H. Buchholz, et al., "Detection and quantitation of bacteria in platelet products stored at ambient temperature," Transfusion 13:268-275 (1973).
D.H. Buchholz, et al., "Bacterial proliferation in platelet products stored at room temperature," New Eng. J. Med. 285:429-433 (1971).
J.F. Morrow, et al., "Septic reactions to platelet transfusions," JAMA 266:555-558 (1991).
G. D. Cimino, et al., "Psoralens as Photoactive Probes of Nucleic Acid Structure and Function: Organic Chemistry, Photochemistry, and Biochemistry," Ann. Rev. Biochem. 54:1151-1193 (1985).
Hearst, et al., "The reaction of the psoralens with deoxyribonucleic acid", Quart. Rev. Biophys. 17:1-44 (1984).
S.T. Isaacs, et al., "Synthesis and Characterization of New Psoralen Derivatives with Superior Photoreactivity with DNA and RNA," Biochemistry 16:1058-1064 (1977).
S.T. Isaacs, et al., "A Photochemical Characterization of Reactions of Psoralen Derivatives with DNA," Trends in Photobiology (Plenum) pp. 279-294 (1982).
J. Tessman, et al., "Photochemistry of the Furan-Side 8-Methoxypsoralen-Thymide Monoadduct Inside the DNA Helix. conversion to Diadduct and to Pyrone-Side Monoadduct," Biochem. 24:16691676 (1985).
H.J. Alter, et al., "Photochemical Decontamination of Blood Components Containing Hepatitis B and Non-A, Non-B Virus," The Lancet ii:1446-1450 (1988).
L. Lin, et al., "Use of 8-Methoxypsoralen and Long-Wavelength Ultraviolet Radiation for Decontamination of Platelet Concentrates," Blood 74:517-525 (1989).
Hyde and Hearst, "Binding of Psoralen Derivatives to DNA and Chromatin: Influence of the Ionic Environment on Dark Binding and Photoreactivity," Biochemistry, 17, 1251-1257 (1978).
Thompson, et al., "Determination of the Secondary Structure of Drosophila Melanogaster 5 S RNA by Hydroxymethyltrimethylpsoralen Crosslinking," J. Mol. Biol., 147:417-436 (1981).
Thompson, et al., "Dependence of 4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen Photoaddition on the Conformation of Ribonucleic Acid," Biochemistry 21:1363-1368 (1982).
P.A. Risticcia and B.A. Cunha, "Klebsiella," Infect. Control 5:343 (1984).
M. Artuc et al. "Reversible binding of 5-and 8-methoxypsoralen to human serum proteins (albumin) and to epidermis in vitro," Brit. J. Derm. 101:669-677 (1979).
M.J. Metzelaar, Studies on the expression of activation-markers on human platelets pp. 73-85 (Thesis 1961).
Gasparro, et al., "Rapid and sensitive analysis of 8-methoxypsoralen in plasma," J. Invest. Dermatol. 90:234-236 (1988).
E. Meek, et al., "Bacerial proliferation in human platelet concentrates stored in plasma or artificial medium," P.F. 1.90 (ISBT) (1988).
Robert M. Knobler MD, et al., "Parenteral administration of 8-methoxypsoralen in photopheresis," J. American Acad. Derm. 28:580-584 (1993).
L. Lin, et al., "Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light," Transfusion 37:423 (1997).
L. Lin, et al., "Photochemical inactivation of pathogenic bacteria in human platelet concentrates," Blood 83:9 pp. 2698-2706 (1994).
L. Lin, et al., "Photochemical inactivation of cell-associated human immunodeficiency virus in platelet concentrates," Blood 82:1 pp. 292-297 (1993).
Corash Laurence
Lin Lily
Carroll Peter G.
Cerus Corporation
Gitomer Ralph
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