Methods of measuring urinary myelin basic protein-like material

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 71, 436501, 436504, 436536, 436540, 436542, 436804, 436811, G01N 3353, G01N 33566, G01N 33567, G01N 33536

Patent

active

059981504

ABSTRACT:
The present invention provides a method of determining the status of a multiple sclerosis patient, i.e., predicting the transition from a status of relapsing-remitting to a progressive phase of multiple sclerosis, comprising the step of measuring the levels of urinary myelin basic protein-like material in the patient. The present invention also provides a method of determining the amount of lesions and total lesion area of a multiple sclerosis patient, comprising the step of measuring the levels of urinary myelin basic protein-like material in the patient. Further provided is a method of monitoring myelination in a developing child, comprising the step of: measuring the levels of myelin basic protein-like material in the urine of said child.

REFERENCES:
patent: 5464777 (1995-11-01), Yip
Tietz, Norbert W. (ed.), Textbook of Clinical Chemistry, W.B. Saunders Company, Philadelphia, pp. 224-226 and 488-489, 1986.
Barry et al., "Myelin Basic Protein Peptides in Urine," Annals of Neurology, 31(3):345-346, Mar. 1992.
Baumhefner et al., "M120. Multiple Sclerosis: Effect of Clinical Disease Activity and Interferon Beta 1-b Treatment on . . . Urinary Myelin Basic Protein-Like Material," Ann. of Neurology, 38(2):315, Aug. 1995.
Deibler et al., "A Reinvestigation of the Amino Acid Sequences of Bovine, Rabbit, Monkey, and Human Myelin Basic Proteins," J. of Biol. Chem. 260(1): 472-474, Jan. 1985.
Gibson et al, "Amino Acid Sequence of Human Myelin Basic Protein Peptide 45-89 As Determined by Mass Spectrometry," J. of Biol. Chem.; 259(8):5028-5031, Apr. 1984.
Giovannoni et al., "Urinary Myelin Basic Protein-like Material as a Correlate of the Progression of Multiple Sclerosis," Ann. of Neurol, 40(1): 128-129, Jul. 1996.
Whitaker et al., "P107. Further Investigation of Urinary Myelin Basic Protein-like Material in Pateints with Multiple Sclerosis," Ann. of Neurol. 26(1): 149-150, Jul. 1989.
Whitaker, "Reply", Ann. of Neurol., 31(3) 346-348, Mar. 1992.
Whitaker et al., "Correlation of Clinical Features and Finding on Cranial Magnetic Resonance Imaging with Urinary Myelin Basic Protein-like Material . . . ", Ann. of Neurol., 35(5): 577-585, May 1994.
Whitaker et al., "Urinary Myelin Basic Protein-like Material as a Correlate of the Progressive Phase of Multiple Sclerosis," Ann. of Neurol. 36(2): 259-260, Aug. 1994.
Whitaker et al., "Reply", Ann. of Neurol., 40(1): 129, Jul. 1996.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of measuring urinary myelin basic protein-like material does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of measuring urinary myelin basic protein-like material, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of measuring urinary myelin basic protein-like material will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-822455

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.