Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1984-08-15
1988-03-15
Warden, Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435291, 435808, 435 26, C12Q 100, C12Q 132, C12M 134
Patent
active
047313234
ABSTRACT:
The present invention relates to methods for measurement and detection which employ a photosensitive indicator which may be prepared from a composition capable of offering a visual, calibrated reaction to the presence of ultraviolet radiation. The indicator preferably employs a composition comprising a complex of a leuco dye and animal-derived serum albumin. The leuco dye-serum albumin complex is capable of exacting calibration, so that scientifically significant quantitative measurements of radiation falling within the wavelengths of ultraviolet light and lower may be made. Numerous techniques useful in a variety of diagnostic applications are made possible, including the measurement of bioactive materials that are independently capable of absorbing ultraviolet wave energy, as well as bioactive materials that by association with certain ancillary materials capable of modulating their ultraviolet light absorption may similarly be quantitatively measured.
REFERENCES:
patent: 1845835 (1932-02-01), Frankenburger et al.
patent: 2325038 (1943-07-01), Chalkley
patent: 2366179 (1945-01-01), Chalkley
patent: 2441561 (1948-05-01), Chalkley
patent: 2528496 (1950-11-01), Chalkley
patent: 2676887 (1954-04-01), Chalkley
patent: 2829052 (1958-04-01), Chalkley
patent: 2829148 (1958-04-01), Chalkley
patent: 2829149 (1958-04-01), Chalkley
patent: 2839542 (1958-06-01), Chalkley
patent: 2839543 (1958-06-01), Chalkley
patent: 2844465 (1958-07-01), Chalkley
patent: 2855303 (1958-10-01), Chalkley
patent: 2855304 (1958-10-01), Chalkley
patent: 2877166 (1959-03-01), Chalkley
patent: 2877167 (1959-03-01), Chalkley
patent: 2877168 (1959-03-01), Chalkley
patent: 2877169 (1959-03-01), Chalkley
patent: 2895892 (1959-07-01), Chalkley
patent: 2936235 (1960-05-01), Chalkley
patent: 2936276 (1960-05-01), Chalkley
patent: 3071464 (1963-01-01), Chalkley
patent: 3122438 (1964-02-01), Chalkley
patent: 3236648 (1966-02-01), Chalkley
patent: 3382074 (1968-05-01), Kimura et al.
patent: 3407065 (1968-10-01), Chalkley
patent: 3837746 (1974-09-01), Acker et al.
patent: 3881992 (1975-05-01), Ralston
patent: 4062713 (1977-12-01), Anderson
patent: 4379840 (1983-04-01), Gorka et al.
patent: 4466941 (1984-08-01), Cerami et al.
Chalkley, L., Photometric Papers Sensitive Only to Short Wave Ultraviolet, Journal of the Optical Society of America 42(6):387-392 (1952).
Chalkley, L., Organic Mercury Derivatives of Basic Triarylmethane Dyes: Dimercuri Derivatives of Malachite Green, J.A.C.S. 63:981-987 (1941).
Miyake, Y., A New Chemical Method for Measuring the Ultra-Violet Ray, Bulletin of the Chemical Society of Japan 22:105-109 (1949).
Harris, L., et al. The Absorption Spectrum of Malachite Green Leucocyanide and the Mechanism of the Dark Reaction After Photolysis, J.A.C.S. 57:1151-1154 (1935).
Harris, L. et al. A Precision Actinometer for the Ultraviolet Region (including an exact text of the Einstein Equivalence Law), J.A.C.S. 57:1154-1159, (1935).
Zweig, A., et al. A Photochemical Mid-Ultraviolet Dosimeter for Practical Use as a Sunburn Dosimeter, Photochemistry and Photobiology 24:543-549 (1976).
Weyde, E., et al. The Measurement of Ultraviolet Radiation, Especially of the Physiologically Active Ultraviolet (which produces erythema), by Means of the Photochemical Formation of Triphenylmethane Dyes from the Leuco Compounds, Transactions of the Faraday Society 27:561-571, Plus Discussion (1931).
Chalkley, L., The Mercuration of Methylene Blue, J.A.C.S. 47:2055-2061 (1925).
Calvert, J. G., et al. Precision Actinometry at Low Light Intensities with Malachite Green Leucocyanide, J.A.C.S. 74:2101-2103 (1952).
Cerami Anthony
Yamin Michael A.
Deck Randall E.
Evreka Inc.
Warden Robert J.
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