Methods of making transgenic animals producing oligosaccharides

Details Methods of making transgenic animals producing oligosaccharides Methods of making transgenic animals producing oligosaccharides

1995-05-02

1997-12-23

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

435 6, 435 691, 435193, 800 2, C12N 1500, C12N 910, C12Q 168, C12P 2106

Patent

active

057006717

ABSTRACT:
The invention relates to transgenic non-human mammals characterized in that the genome of said mammals contain at least one heterologous gene encoding for the production of heterologous catalytic entity selected from the group consisting of enzymes and antibodies, and wherein said catalytic entity produces a second heterologous product in the milk of said mammal. Especially useful in the practice of the invention are human glycosyltransferases and transgenic sheep, goats and cows. The heterologous product includes oligosaccharides and glycoconjugates.

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