Methods of making microarrays with substrate surfaces having...

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C530S350000, C530S387100, C536S023100, C536S024310, C536S024330

Reexamination Certificate

active

06989267

ABSTRACT:
Methods for stably associating a polyelectrolyte coating or film to a substrate surface, as well as the coated substrates produced thereby, are disclosed herein. In the subject methods, substrate surfaces are coated with a polyelectrolyte, and the coated substrate surfaces are treated with a bifunctional molecule under conditions sufficient to stably associate the film to the array surface. The subject methods find use in a variety of different applications, including the production of mircoarrarys.

REFERENCES:
patent: 5250613 (1993-10-01), Bergstrom et al.
patent: 5629213 (1997-05-01), Kornguth et al.
patent: 5807522 (1998-09-01), Brown et al.
patent: 5858671 (1999-01-01), Jones
patent: 6110426 (2000-08-01), Shalon et al.
patent: WO 00/65352 (2000-11-01), None

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