Methods of making amidino compounds useful as nitric oxide...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C548S317100, C560S148000, C562S557000

Reexamination Certificate

active

07102013

ABSTRACT:
Method of making an alpha-amino acid compound having the structure of Formula 32:comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33:where the substituents are described herein.

REFERENCES:
patent: 5132453 (1992-07-01), Griffith
patent: 5608076 (1997-03-01), Kottenhahn et al.
patent: 5684008 (1997-11-01), Hallinan et al.
patent: 5830917 (1998-11-01), Moore et al.
patent: 5854251 (1998-12-01), Hallinan et al.
patent: 5863931 (1999-01-01), Beams et al.
patent: 5919787 (1999-07-01), Hallinan et al.
patent: 5945408 (1999-08-01), Webber et al.
patent: 5981511 (1999-11-01), Gapud et al.
patent: 5994391 (1999-11-01), Lee et al.
patent: 6355689 (2002-03-01), Beswick et al.
patent: 0446699 (2000-05-01), None
patent: 0521471 (2000-10-01), None
patent: WO9313055 (1993-07-01), None
patent: WO9316055 (1993-08-01), None
patent: WO9412165 (1994-06-01), None
patent: WO9414780 (1994-07-01), None
patent: WO9511014 (1995-04-01), None
patent: WO9511231 (1995-04-01), None
patent: WO9525382 (1995-09-01), None
patent: WO9525717 (1995-09-01), None
patent: WO615120 (1996-05-01), None
patent: WO9633175 (1996-10-01), None
patent: WO9635677 (1996-11-01), None
patent: WO9706802 (1997-02-01), None
patent: WO9929865 (1999-06-01), None
patent: WO9946240 (1999-09-01), None
patent: WO9962875 (1999-12-01), None
S. Moncada E. Higgs Molecular Mechanisms and Therapeutic Strategies Related to Nitric Oxide 1995, FASEB, J.,9, 1319-1330.
S. Tozen, et al. Organic Fluorine Compounds Part XLIV. Preparation and Reactions of Epifluorohydrin 1971, Synthesis 646-647.
E. Bergmann, et al. Organic Fluorine Compounds Part XX. Some Reactions of 1-Chloro-3-fluoropropan-2-ol and Epifluorohydrin 1961, J Chem Soc 3448-3452.
A Jeanguenat S. Seebach Stereoselective Chain Elongation at C-3 of Cysteine through 2,3-Dihydrothiazoles, Without Racemization. Preparation of 2-Amino-5-hydroxy-3-mercapto alkanoic Acid Derivatives. 1991, J. Chem. Soc. Perkin Trans. 1, 2291-2298.
G. Pattenden, et al. Enantioselective Synthesis of 2-Alkyl Substituted Cysteines. 1993, Tetrahedron, 49, 2131-2138.
D. Bredt S. Snyder Isolation of Nitric Oxide Synthetase, a Calmodulin-Requiring Enzyme. 1990 Proc. Natl. Acad. Sci. U.S.A., 87, 682-685.
Moore et al. 2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms 1996 J. Med. Chem., 39, 669-672.
T. Misko et al. A Fluorometric Assay for the Measurement of Nitrite in Biological Samples 1993, Analytical Biochemistry, 214, 11-16.
R. J. Young, et al. “Inhibition of Inducible Nitric Oxide Synthase by Acetamidine Derivatives of Hetero-substituted Lysine and Homolysine,” Mar. 2000 Bioorganic and Medicinal Chemistry Letters, vol. 10 597-600.
W. Reid, et al. “Amidinosäuren Und Imedopeptide,” Mar. 1962 Chemische Berichte, Vol 95, 728-732.
U.K. Saha, et al. “Synthesis of New Glycopeptidomimetics Based on N-Substituted Oligoglycine Bearing an N-Linked Lactoside Side-chain,” Dec. 21, 1995 Journal of the Chemical Societ, Chemical Communications, 2571-2573.
W. König, et al. “Neue S-Shutzgruppen fúr Cystein,”, 1968 Chemische Berichte, Vol 101 681-693.
C. Dugave, et al. “Synthesis of Natural and Non Natural Orthoganally Protected Lanthionines from N-Tritylserine and Allo-Threonine Derivatives,” May 8, 1997 Tetrahedron: Asymmetry vol 8, 1453-1465.
N.G. Kimpe, et al. “Novel Synthesis of 5-Acetyl-2, 3-Dihydro-1, 4-Thiazine, A Very Intense Roasty, Popcornlike Odorant,” May 29, 1998 Journal of Agricultural and food Chemistry, vol. 46, 2278-2281.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of making amidino compounds useful as nitric oxide... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of making amidino compounds useful as nitric oxide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of making amidino compounds useful as nitric oxide... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3557258

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.