Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-10-21
2009-11-24
Kolker, Daniel E. (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S387900
Reexamination Certificate
active
07622270
ABSTRACT:
A novel gene 65B13 expressed specifically and transiently in dopaminergic neuron precursor cells immediately after cell cycle exit was obtained by the present invention. The cellular expression of 65B13 can be used as an index to select cells that are suitable in terms of their safety, survival rate, and network formation ability, for transplant therapy of neurodegenerative diseases such as Parkinson's disease.
REFERENCES:
patent: 7304145 (2007-12-01), Goddard et al.
patent: 2002/0068045 (2002-06-01), Reubinoff et al.
patent: 2002/0127584 (2002-09-01), Baker et al.
patent: 2002/0155423 (2002-10-01), Okano et al.
patent: 2003/0036150 (2003-02-01), Baker et al.
patent: 2003/0109039 (2003-06-01), Buck et al.
patent: 2004/0241170 (2004-12-01), Jensen et al.
patent: 2007/0254281 (2007-11-01), Ono et al.
patent: 2 315 538 (1999-07-01), None
patent: 2001-526884 (2001-12-01), None
patent: WO 94/23754 (1994-10-01), None
patent: WO 01/92482 (2001-12-01), None
patent: WO 01/98360 (2001-12-01), None
patent: WO 01/98360 (2001-12-01), None
patent: WO 2004/065599 (2004-08-01), None
Sun (2003) Genomics 82(2):130-142.
Genbank Accession No. AF296764, “Mus musculus nephrin (Nphs1) gene, 5′ flanking region, 5′ UTR.”, Aug. 16, 2000.
Genbank Accession No. AC002133, “Human DNA from chromosome 19 cosmid R33502, genomic sequence.”, Jun. 3, 1997.
Genbank Accession No. BCO52773, “Mus musculus kin of IRRE like 2 (Drosophila), mRNA (cDNA clone MGC:56936 Image:6314924)”, May 23, 2003.
Björklund, Lars M. et al.; “Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model”;PNAS;Feb. 19, 2002; pp. 2344-2349; vol. 99, No. 4.
Björklund, Anders et al.; “Neural transplantation for the treatment of Parkinson's disease”;The Lancet: Neurology;Jul. 2003; pp. 437-445; vol. 2.
Kim, Tai Eun et al.; “Cloning and cell type-specific regulation of the human tyrosine hydroxylase gene promoter”;Biochemical and Biophysical Research Communications;2003; pp. 1123-1131; vol. 312.
Yan, Jun et al.; “Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors”;Journal of Neurochemistry;2001; pp. 307-311; vol. 76.
Alberts, B., et al.,Molecular Biology of the Cell,pp. 104-111, Third Edition (1994).
Huber, Tobias B. et al.; “The carboxyl terminus of Neph family members binds to teh PDZ domain protin zolula occludens-1”;The Journal of Biological Chemistry;Apr. 11, 2003; pp. 13417-13421; vol. 278, No. 15.
Ihalmo, Pekka et al.; “Filtrin is a novel member of nephrin-like proteins”;Biochemical and Biophysical Research Communications;2003; pp. 364-370; vol. 300.
Kawasaki, Hiroshi et al.; “Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity”;Neuron;Oct. 2000; pp. 31-40; vol. 28.
Kim, Jong-Hoon et al.; “Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease”;Nature;Jul. 4, 2002; pp. 50-56; vol. 418.
Kordower, J. H. et al.; “Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease”;N. Engl. J. Med.;Apr. 27, 1995; pp. 1118-1124; vol. 332, No. 17.
Lisitsyn, N. A.; “Representational difference analysis: finding the differences between genomes”;Trends Genet.;Aug. 1995; pp. 303-307; vol. 11, No. 8.
Sakurada, Kazuhiro et al.; “Seitai Shinkei Kansaibo Bunka no Bunshi Mechanism”;Cell Technology;2000; pp. 398-405; vol. 19, No. 3 (In Japanese).
Sakurada, Kazuhiro et al.; “Seitai Shinkei Kansaibo o Hyoteki to shita Saisei lryo”;The Tissue Culture Engineering;2000; pp. 303-306; vol. 26, No. 8 (In Japanese).
Sawamoto, Kazunobu et al.; “Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled withnestin-GFPtransgene”;The Journal of Neuroscience;Jun. 1, 2001; pp. 3895-3903; vol. 21, No. 11.
Sawamoto, Kazunobu et al.; “Visualization, direct isolation, and transplantationof midbrain dopaminergic neurons”;PNAS;May 22, 2001; pp. 6423-6428; vol. 98, No. 11.
Sellin, Lorenz etal.; “NEPH1 defines a novel family of podocin interacting proteins”;FASEB J.;Jan. 2003; pp. 115-117; vol. 17.
Studer, Lorenz et al.; “Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats”;Nature Neuroscience;Aug. 1998; pp. 290-295; vol. 1, No. 4.
Di Porzio, et al., “Dopaminergic neurons from embryonic mouse mesencephalon are enriched in culture through immunoreaction with monoclonal antibody to neural specific protein 4 and flow cytometry,”Proc Natl Acad Sci U.S.A.,1987, vol. 84, No. 20, pp. 7334-8.
Shinmura, Comprehensive Dictionary of the Japanese Language (Kojien), 1998, 5th Ed. pp. 1466.
Mizuhara Eri
Nakagawa Yasuko
Nakatani Tomoya
Ono Yuichi
Sakamoto Yoshimasa
Eisai R&D Management Co., Ltd.
Kolker Daniel E.
Townsend and Townsend / and Crew LLP
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