Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2001-04-05
2009-02-03
Kam, Chih-Min (Department: 1656)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S012200, C530S350000, C530S387100, C424S130100, C424S009100
Reexamination Certificate
active
07485616
ABSTRACT:
The present invention provides a therapeutic method for removing amyloid fibrils from a patient. The present invention also provides a transgenic animal that develops systemic AA amyloidosis within three weeks for use as a tool to investigate AA amyloidosis and to evaluate agents that may be potentially useful in preventing and treating amyloid-related disorders. Further, the present invention provides diagnostic assays for monitoring immunoglobulin light chain fibrillogenesis in real-time and for identification of the chemical nature of the protein in amyloid deposits which enables the determination of the type of amyloidosis for therapeutic and prognostic purposes.
REFERENCES:
patent: 4828563 (1989-05-01), Muller-Lierheim
patent: 5583005 (1996-12-01), Nishimura et al.
patent: 5643570 (1997-07-01), Theofan et al.
patent: 5750106 (1998-05-01), Ostberg et al.
patent: 6875434 (2005-04-01), Schenk
patent: 2002/0019335 (2002-02-01), Solomon et al.
patent: 91/16819 (1991-11-01), None
patent: 95/12815 (1995-05-01), None
patent: 95/31996 (1995-11-01), None
patent: WO 96/25435 (1996-08-01), None
patent: 99/27944 (1999-06-01), None
patent: 99/60024 (1999-11-01), None
patent: 00/72876 (2000-12-01), None
Helmuth, L.; “Further Progress on a β-Amyloid Vaccine”; Science, vol. 289, No. 5478, Jul. 21, 2000, pp. 349-496.
Schenk et al.; Immunication with amyyloid-β anntenuates Alzheimer-disease-like pathology in the PDAPP mouse, Nature, vol. 400, No. 6740, Jul. 8, 1999, pp. 173-177.
Hrncic Rudi
Schell Maria
Solomon Alan
Wall Jonathan Stuart
Kam Chih-Min
Morgan & Lewis & Bockius, LLP
University of Tennessee Research Foundation
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