Methods of inhibiting T cell mediated immune responses with huma

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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4241301, 4241331, 4241411, 4241431, 4241441, 4241531, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875, 435 696, 435 7021, 435452, 435328, 435332, 435343, 4353431, 4353432, 536 2353, A61K 39395, C07K 1628, C12N 512, C07H 2104

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059519835

ABSTRACT:
The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.

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