Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1995-06-07
1999-09-14
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241301, 4241331, 4241411, 4241431, 4241441, 4241531, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875, 435 696, 435 7021, 435452, 435328, 435332, 435343, 4353431, 4353432, 536 2353, A61K 39395, C07K 1628, C12N 512, C07H 2104
Patent
active
059519835
ABSTRACT:
The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.
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Bazin Herve
Kaplan Ruth
Kieber-Emmons Thomas
Latinne Dominique
Postema Christina E.
Bio Transplant, Inc.
Chan Christina Y.
Gambel Phillip
Lillie Raymond J.
Olstein Elliot M.
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