Methods of inhibiting restenosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 54, 536103, A61K 3170, C08B 3702, C08B 3716

Patent

active

056375751

ABSTRACT:
Disclosed are compositions and methods effective for inhibiting restenosis. In particular, the present invention provides compositions for inhibiting undesired smooth muscle cell growth or proliferation following angioplasty in mammals, said composition comprising active agents comprising a very water-soluble derivative of cyclodextrin. The invention also provides methods of inhibiting undesired smooth muscle cell growth or proliferation following angioplasty in mammals comprising orally administering to the mammal a growth-inhibiting amount of an active agent comprising a very water-soluble derivative of cyclodextrin.

REFERENCES:
patent: 3420788 (1969-01-01), Solms
patent: 4020160 (1977-04-01), Bernstein et al.
patent: 4066829 (1978-01-01), Nair et al.
patent: 4247535 (1981-01-01), Lewis et al.
patent: 4258180 (1981-03-01), Lewis et al.
patent: 4383992 (1983-05-01), Lipari
patent: 4582900 (1986-04-01), Brandt et al.
patent: 4596795 (1986-06-01), Pitha
patent: 4727064 (1988-02-01), Pitha
patent: 4764604 (1988-08-01), Muller
patent: 4834985 (1989-05-01), Elger et al.
patent: 4840941 (1989-06-01), Ueno et al.
patent: 4877774 (1989-10-01), Pitha et al.
patent: 4877778 (1989-10-01), Carpenter et al.
patent: 4902788 (1990-02-01), Zemel et al.
patent: 4929602 (1990-05-01), Harker et al.
patent: 5019562 (1991-05-01), Folkman et al.
The Merck Manual 15.sup.th Ed. (1987) pp. 386-389.
Folkman et al; Science 24:1490-3 (Mar. 1989).
Yamamoto et al; Int. J. Pharm. 49:163-171 (1989).
Powell et al., Low Molecular Weight Heparin Reduces Restenosis After Experimental Angioplasty, Circulation, supp. II. vol. 80, No. 4 (Oct. 1989).
Croft et al., Tetrahedron, vol. 39, pp. 1417-1474 (1983).
LeVeen et al., Investigative Radiology, 17:470-475 (1982).
Nakashima et al., Antimicrobial Agent and Chemotherapy, pp. 1524-1528 (1987).
Uekama et al., International Journal of Pharmaceutics, vol. 10, pp. 1-15 (1982).
J. Pitha et al., Journal of Pharmaceutical Sciences, vol. 75(2), pp. 165-167 (1986).
Yamamoto et al., International Journal of Pharmaceutics, vol. 49, pp. 163-171 (1989).
Chemical Abstracts, 96:218351u (1982).
Fenyvesi et al., Chem. Pharm. Bull., vol. 32(2), pp. 665-669 (1984).
Fenyvesi et al., Chem. Pharm. Bull., vol. 32(2), pp. 670-677 (1984).
Komiyama et al., Polymer Journal, vol. 18(4), pp. 375-377 (1986).
Herrmann, H.C., Abstracts of Papers, National Meeting of the American Heart Association, Anaheim, CA; Nov. 11-14, 1991.
Chemical Abstracts 83:79544a (1975).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of inhibiting restenosis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of inhibiting restenosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of inhibiting restenosis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-764726

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.