Methods of inhibiting musculoaponeurotic fibromatoses (desmoid t

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514443, A61K 31445, A61K 3138

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active

056705239

ABSTRACT:
A method of inhibiting musculoaponeurotic fibromatoses comprising administering to a mammal in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR2## wherein Ar is, optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

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Evans et al., Endocrinology 134(5), pp. 2282-2288 (Biosis abstract No. 97274419). 1994.

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