Methods of inhibiting metastasis

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S138100

Reexamination Certificate

active

06949243

ABSTRACT:
Methods of inhibiting metastasis or maintenance of various cancers are provided. In particular, the method makes use of fact that certain trafficking of cancers depend upon identified proteins, which serve as markers. Additional methods of screening are also provided.

REFERENCES:
patent: EP 0897980 (1999-02-01), None
patent: WO 96/06169 (1996-02-01), None
patent: WO 98/11218 (1998-03-01), None
patent: WO 99/47158 (1999-09-01), None
patent: WO 00/38713 (2000-07-01), None
patent: WO 00/46248 (2000-08-01), None
Negus RP et al World J Urol 1996;14(3):157-65.
Wang et al J. Immunol Meth 1998;220:1-17.
Mohle et al (Blood Jun. 15, 1998;91(21):4523-4530).
Loetscher et al (J. Biol. Chem. Aug. 28, 1998:273(35):22279-22283).
The On-line Medical Dictionary is ©Academic Medical Publishing & The CancerWEB Project 1997-2002 http://medical-dictionary.com/ Nov. 18, 1997.
Fujisawa N et al. (Melanoma Res Apr. 9, 1999(2):105-114).
Freshney (Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p4).
Dermer (Bio/Technology, 1994, 12:320).
A. Aiuti, et al.,Journal of Experimental Medicine,185:111-120, 1997. “The Chemokine SDF-1 Is a Chemoattractant for Human CD34+Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+Progenitors to Peripheral Blood”.
Kevin Beaumont and Paul Negulescu,Nature biotechnology,17:1060-1108, 1999. “Chipping Away at GPCR Function”.
Christopher Bieri, et al.,Nature Biotechnology,17:1105-1108, Nov. 1999. “Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation”.
M. Birkenbach, et al.,Genbank,Accession No. NM—001838, Oct. 31, 2000 “Homo sapienschemokine (C-C motif) receptor 7 (CCR7), mRNA.”
Barak A. Cohen, et al., 95:14272-14277, 1998. “An artificial cell-cycle inhibitor isolated from a combinatorial library”.
B. Federsppiel, et al.,Genbank, Accession No. NM—003467, Nov. 1, 2000. “Homo sapiens chemokine (C-X-C motif), receptor 4 (fusin) (CXCR4), mRNA.”.
Jorg Kleeff, et al.,International Journal of Cancer, 81:650-657, 1999. “Detection and Localization of MIP-3alpha/LARC/EXODUS, a m,acrophage proinlammatory chemokine, and its CCR6 receptor in human pancreatic cancer”.
Mikhail G. Kolonin and Russell L Finley, Jr.,Proceedings of the National Academy of Sciences, 95:14266-14271, 1998. “Targeting cyclin-dependent kinases inDrosophilawith peptide aptamers”.
Simon F. Lacey, et al.Proceedings of the National Academy of Sciences, 94:9842-9847 1997. “The CXC chemokine stromal cell-derived factor 1 is not responsible for CD8+T cell suppression of syncytia-inducing strains of HIV-1”.
A. Marchese, et al.,Genbank, Accession No. U13667, Apr. 1, 1995. “Human G protien-coupled receptor (GPR2) gene, partial cds”.
M. Marra, et al.,Genbank, Accession No. AA620142, Oct. 9, 1997. “vo63a06.r1 Soares—mammary—gland—NbMMG Mus musculus cDNA clone IMAGE:1054546 5′ similar to gb:L12030 Mus musculus cytokine (MOUSE);, mNRNA sequence gi|2524018|gb|AA620142.1|AA620142[2524018]”.
B. Moser,Gennbank,Accession No. X71635, Feb. 15, 1994. “H.sapiens mRNA for neuropedtide Y-like receptor.”
D. Rossi, et al.,GenBank, Accession No. U77180, Jan. 23, 1997. “Human macrophage inflammatory protein 3 beta (MIP-3beta) mRNA, complete cds.”
Thomas J. Schall and Kevin B. Bacon,Current Opinion in Immunology,6:865-873, 1994. “Chemokines, leukocyte trafficking, and inflammation”.
V.L Schweickart,GenbankAccession No. L—31581, Aug. 10, 1995. “Human G protein-coupled receptor (EBI 1) mRNA, complete cds.”
Robert Strausberg,GenbankAccession No. AI670734, May 18, 1999. “SW:GPR2—Human P46092 Probable G Protein-Coupled Receptor GPR2.”
K. Tashiro, et al.GenBank, Accession No. L12030, Sept. 3, 1993. “Mus musculus cytokine (SDF-1-beta) mRNA, complete cds.”
Sara J. Youngs, et al.,International Journal of Cancer, 71: 257-266, 1997. “Chemokines Induce Migrational Responses in Human Breast Carcinoma Cell Lines”.
Muller et al., Involvement of chemokine receptors in breast cancer metastasis. Nature. Mar. 1, 2001:410(6824):50-56.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of inhibiting metastasis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of inhibiting metastasis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of inhibiting metastasis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3372217

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.