Methods of inducing hair growth and coloration

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S012200, C514S017400, C514S015800

Reexamination Certificate

active

06867179

ABSTRACT:
Methods to control, or manipulate, melanocyte and keratinocyte cell death are disclosed. In particular, a method of preventing epidermal melanocyte cell loss due to injury in a vertebrate is disclosed. Also disclosed is a method of inducing hair growth in a vertebrate, a method of inducing hair color in a vertebrate, a method of inducing skin color in a vertebrate, a method of treating baldness in an individual, and a method of treating alopecia areata in an individual.

REFERENCES:
patent: 4621023 (1986-11-01), Redziniak et al.
patent: 5077211 (1991-12-01), Yarosh
patent: 6242416 (2001-06-01), Gilchrest et al.
patent: 0 584 452 (1994-03-01), None
patent: 63183518 (1988-07-01), None
patent: 63301810 (1988-12-01), None
patent: 11 029441 (1999-02-01), None
patent: WO 9218149 (1992-10-01), None
patent: WO 9521193 (1995-08-01), None
patent: WO 9606633 (1996-03-01), None
patent: WO 9612955 (1996-05-01), None
patent: WO 9737228 (1997-10-01), None
Zhai, S., et al., “A Role for P75 Nerve Growth Factor Receptor in Programmed Melanocyte Cell Death After Injury and With Aging,”Journal of Investigative Dermatology, 102(4):545, SID Abstract #131 (1994).
Yaar, M., et al., “Cloning and Expression of a Novel Nerve Growth Factor Related Molecule in Human Skin,”Journal of Investigative Dermatology, 100:(4):548, Abstract #100 (1993).
Yaar, M., et al., “Melanocyte Function in Human Skin is Modulated by Neurotrophic Factors through TRK Receptors,”Journal of Investigative Dermatology, 100(4):511, Abstract #134 (1993).
Zhai, S., et al., “Nerve Growth Factor (NGF) Enhances Survival of Human Melanocytes,”Journal of Investigative Dermatology, 101:434, Abstract #279 (1993).
Yaar, M., et al., “Involvement of TRK Proto-Oncogene in Physiologic Stimuli of Human Melanocytes,”Clinical Research, 40(2):531A, SID Abstracts, (1992).
Price, V.H., “Alopecia Areata: Clinical Aspects,”Journal of Investigative Dermatology, 96(5), Supplement:68S (19991).
Yaar, M., et al., “Human Melanocyte Growth and Differentiation: A Decade of New Data,”Journal of Investigative Dermatology, 97(4):611-617 (1991).
Goldsmith, L.A., “Summary of Alopecia Areata Research Workshop and Future Research Directions,”Journal of Investigative Dermatology, 96(5), Supplement:98S-100S (1991).
Friedmann, P.S., “Clinical and Immunologic Associations of Alopecia Areata,”Seminars in Dermatology, 4(1):9-15 (1985).
Stenn, K.S., et al., “Expressing of the bcl-2 Protooncogene in the Cycling Adult Mouse Hair Follicle,”Journal of Investigative Dermatology, 103(1):107-111 (1994).
Rabizadeh, S., et al., “Induction of Apoptosis by the Low-Affinity NGF Receptor,”Science, 261:345-348 (1993).
Garcia, I., et al., “Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene,”Science, 258:302-304 (1992).
Allsopp, T.E., et al., “The Proto-Oncogene bcl-2 Can Selectively Rescue Neurotrophic Factor-Dependent Neurons from Apoptosis,”Cell, 73:295-307 (1993).
Veis, D.J., et al., “Bcl-2-Deficient Mice Demonstrate Fulminant Lymphoid Apoptosis, Polycystic Kidneys, and Hypopigmented Hair,”Cell75:229-240 (1993).
DiMarco, E., et al., “Growth-regulated Synthesis and Secretion of Biologically Active Nerve Growth Factor by Human Keratinocytes,”Journal of Biological Chemistry, 266(32):21718-21722 (1991).
Yaar, M., et al,. “Evidence for Nerve Growth Factor-mediated Paracrine Effects in Human Epidermis,”Journal of Cell Biology115(3):821-828 (1991).
Barinaga, M., “Death Gives Birth to the Nervous System. But How?”Science, 259:762-763 (1993).
Hockenbery, D.M., et al., “Bcl-2 Functions in an Antioxidant Pathway to Prevent Apoptosis,”Cell, 75:241-251 (1993).
Di Marco, E., et al., “Molecular Cloning of trkE, a Novel trk-related Putative Tyrosine Kinase Receptor Isolated from Normal Human Keratinocytes and Widely Expressed by Normal Human Tissues,”Journal of Biological Chemistry, 268(32):24290-24295 (1993).
Peacocke, M., et al., “Induction of nerve growth factor receptors on cultured human melanocytes,”Proc. Natl. Acad. Sci. USA, 85:5282-5286 (1988).
Barinaga, M., “Cell Suicide: By ICE, Not Fire,”Science, 263:754-756 (1994).
Paus, R., et al., “Telogen skin contains an inhibitor of hair growth,”British Journal of Dermatology, 122:777-784 (1990).
Ross, A.H., et al., “Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies,”Proc. Natl. Acad. Sci. USA, 81:6681-6685 (1984).
Halaban, R., et al., “Basic Fibroblast Growth Factor from Human Keratinocytes Is A Natural Mitogen for Melanocytes,”Journal of Cell Biology, 107:1611-1619 (1988).
Halaban, R., et al., “bFGF is the Putative Natural Growth Factor For Human Melanocytes,”In Vitro Cellular&Development Biology, 23(1):47-52 (1987).
Ullrich, A., et al., “Human β-nerve growth factor gene sequence highly homologous to that of mouse,”Nature, 303:821-825 (1983).
Morgenstern, J.P., et al., “Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line,”Nucleic Acids Research, 18(12):3587-3596 (1990).
Johnson, D., et al., “Expression and Structure of the Human NGF Receptor,”Cell, 47:545-554 (1986).
Heuer, J.G., et al., Structure and Development Expression of the Chicken NGF Receptor,Development Biology, 137:287-304 (1990).
Large, T.H., et al., “Structure and Developmental Expression of the Nerve Growth Factor Receptor in the Chicken Central Nervous System,”Neuron, 2:1123-1134 (1989).
Radeke, M.J., et al., “Gene transfer and molecular cloning of the rat nerve growth factor receptor,”Nature, 325:593-597 (1987).
Mitchell, A.J., et al., “Alopecia areata: Pathogenesis and treatment,”Journal of the American Academy of Dermatology, 11(5)1:763-775 (1984).
Klein, R., et al., “The trk Proto-Oncogene Encodes a Receptor for Nerve Growth Factor,”Cell, 65:189-197 (1991).
Maisonpiere, P.C., et al., “Neurotrophin-3: A Neurotrophic Factor Related to NGF and BDNF,”Science, 247:1446-1451 (1990).
Chao, M.V., et al., “Gene Transfer and Molecular Cloning of the Human NGF Receptor,”Science, 232:518-521 (1986).
Headington, J.T., “Transverse Microscopic Anatomy of the Human Scalp,”Arch. Dermatol., 120:449-456 (1984).
Sperling, L.C., “Hair anatomy for the children,”Journal of the American Academy of Dermatology, 25(1):1-17 (1991).
Gilchrest, B.A., “Skin and Aging Processes,” (Boca Raton, FL.,CRC Press, Inc.) pp. 19-20 (1984).
Bertolino, A.P., et al., “Biology of Hair Follicles,InDermatology in General Medicine,” Thomas B Fitzpatrick et al. (Ed.), Section 4, Chapter 19, (NY: McGraw-Hill, Inc.) pp. 289-293, Fourth Edition, (1993).
Bertolino, A.P., et al., “Hair,” InDermatology in General Medicine, Thomas B. Fitzpatrick et al. (Ed.), Section 10, Chapter 61, (NY: McGraw-Hill, Inc.) pp. 671-673, Fourth Edition, (1993).
Marchetti, D., et al, “Nerve Growth Factor Effects on Human and Mouse Melanoma Cell Invasion and Heparanase Production,”Int. J. Cancer, 55:692-699 (1993).
Spritz, R.A., et al., “Inhibition of Proliferation of Human Melanocytes by a KIT Antisense Oligodeoxynucleotide: Implications for Human Piebaldism and Mouse Dominant White Spotting (W),”J. Invest. Dermatology, 103(2):148-150 (1994).
Nataraj, A., et al., “bcl-2 Oncogene Blocks Differentiation and Extends Viability But Does Not Immortalize Normal Human Keratinocytes,”Intl. J. Oncology, 4:1211-1218 (1994).
Nakayama, K., et al., “Targeted Disruption of Bcl2αβ in Mice: Occurrence of Gray Hair, Polycystic Kidney Disease, and Lymphocytopenia,”Proc. Natl. Ac

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of inducing hair growth and coloration does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of inducing hair growth and coloration, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of inducing hair growth and coloration will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3419106

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.