Methods of increasing tolerance to radiotherapy and chemotherapy

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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424 92, 4241951, 378 65, A61K 3574

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active

046474560

ABSTRACT:
It has been found that compositions derived from Propioni bacteria, especially P. granulosum, P. avidium, and P. acnes are useful in increasing tolerance of individuals to radiotherapy and chemotherapy. When these compositions are administered before or during a regimen of radio- or chemotherapy, the subject can receive higher doses of radiation and chemicals without harmful side effects.

REFERENCES:
Saino et al.-Chem. Abst., vol. 85 (1976), p. 2259v.
Szmigielski et al-Zentralbl. Bacteriol, vol. 248, No. 3 (1980), pp. 286-295.
Roszkowski et al-Med.Mikrobiol Infektionskr Parasitol, vol. 246, No. 3 (1980), pp. 393-404.
Azuma et al-Chem. Abst., vol. 86 (1977), p. 3460m.

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