Methods of immunopurification of antigens of human immunodeficie

Details Methods of immunopurification of antigens of human immunodeficie Methods of immunopurification of antigens of human immunodeficie

1992-08-14

1994-11-15

Nucker, Christine M.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

530826, 4352351, 435239, 435974, C07K 312, C07K 1504

Patent

active

053649338

ABSTRACT:
The invention relates to a new variety of retroviruses designated Human Immunodeficiency Virus Type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I-532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis and kits, in particular by being placed in contact with serum of the patient to be diagnosed. Lastly, the invention relates to immunizing compositions, in particular containing at least one of glycoproteins gp 36 and gp 130-140.

REFERENCES:
patent: 4708818 (1987-11-01), Montagnier et al.
patent: 4839288 (1989-06-01), Montagnier et al.
Clavel et al: "Virology-LAV type II: A Second Retrovirus Associated with AIDS in West-Africa" C. R. Acad Sc 302 485-88 (1986).

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