Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1994-11-07
1999-12-21
Burke, Julie
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
424 91, 4241331, 4241381, 4241411, 424 149, 435 71, 435 792, 435 723, 435 793, 5303871, 5303881, 5303882, A61K 39395, A61K 4900, A61K 5108, G01N 3348
Patent
active
060045353
ABSTRACT:
A new gene--MN--and proteins/polypeptides encoded therefrom are disclosed. Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and fusion proteins are provided. Expression of the MN gene is disclosed as being associated with tumorigenicity, and the invention concerns methods and compositions for detecting and/or quantitating MN antigen and/or MN-specific antibodies in vertebrate samples that are diagnostic/prognostic for neoplastic and pre-neoplastic disease. MN-specific antibodies are disclosed that can be used diagnostically/prognostically, therapeutically, for imaging, and for affinity purification of MN proteins/polypeptides.
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Pastorek Jaromir
Pastorekova Silvia
Zavada Jan
Burke Julie
Institute of Virology Slovak Academy of Sciences
Lauder Leona L.
Morgenstern Arthur S.
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