Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-02-27
2007-02-27
Strzelecka, Teresa (Department: 1637)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S024100, C435S320100
Reexamination Certificate
active
10182329
ABSTRACT:
Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating the oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements.
REFERENCES:
patent: 5686120 (1997-11-01), Mertz et al.
patent: WO 94/24870 (1994-11-01), None
patent: WO 99/02719 (1999-01-01), None
patent: WO 99/25817 (1999-05-01), None
Chappell Stephen A.
Edelman Gerald M.
Jones Frederick S.
Mauro Vincent P.
Meech Robyn
DLA Piper (US) LLP
Strzelecka Teresa
The Scripps Research Institute
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