Methods of identifying modulators of the FGF receptor

Details Methods of identifying modulators of the FGF receptor Methods of identifying modulators of the FGF receptor

2006-09-19

2006-09-19

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C702S019000, C702S020000

Reexamination Certificate

active

07108984

ABSTRACT:
The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.

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