Methods of identifying melanin concentrating hormone...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007100, C435S007200, C435S252300, C435S320100, C435S361000, C435S336000, C435S357000, C435S365000, C530S350000, C536S023500

Reexamination Certificate

active

10825581

ABSTRACT:
This invention provides an isolated nucleic acid encoding a human MCH1 receptor, a purified human MCH1 receptor, vectors comprising isolated nucleic acid encoding a human MCH1 receptor, cells comprising such vectors, antibodies directed to a human MCH1 receptor, nucleic acid probes useful for detecting nucleic acid encoding human MCH1 receptors, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding human MCH1 receptors, transgenic, nonhuman animals which express DNA encoding a normal or mutant human MCH1 receptor, methods of isolating a human MCH1 receptor, methods of treating an abnormality that is linked to the activity of a human MCH1 receptor, as well as methods of determining binding of compounds to mammalian MCH1 receptors.

REFERENCES:
patent: 6008012 (1999-12-01), Bergsma et al.
patent: 6033872 (2000-03-01), Bergsma et al.
patent: 6221613 (2001-04-01), Salon et al.
patent: 6221616 (2001-04-01), Salon et al.
patent: 6291195 (2001-09-01), Salon et al.
patent: 6362326 (2002-03-01), Sathe et al.
patent: 848060 (1998-06-01), None
patent: WO9618651 (1996-06-01), None
patent: WO9639162 (1996-12-01), None
patent: WO9815570 (1998-04-01), None
patent: WO9928492 (1999-06-01), None
patent: 0015793 (2000-03-01), None
patent: 0040725 (2000-07-01), None
patent: 0075166 (2000-12-01), None
patent: WO0105947 (2001-01-01), None
patent: 0121169 (2001-03-01), None
patent: 0121577 (2001-03-01), None
patent: 0143759 (2001-06-01), None
patent: 0157070 (2001-08-01), None
patent: 0168706 (2001-08-01), None
patent: 0203070 (2002-01-01), None
patent: WO 02/02744 (2002-01-01), None
U.S. Appl. No. 09/885,478, filed Jun. 20, 2001 (Exhibit 1).
Borowsky, Beth, et al., DNA Encoding A Human Melanin Concentrating Hormone Receptor (MCHI) And Uses Thereof. U.S. Appl. No. 09/899,732, filed Jul. 5, 2001.
Forray, Carlos, et al., DNA Encoding A Human Melanin Concentrating Hormone Receptor (MCHI) And Uses Thereof. U.S. Appl. No. 10/029,314, filed Dec. 20, 2001.
U.S. Appl. No. 10/341,751, filed Jul. 14, 2003 (Exhibit 2).
Expressed Sequence Tags Database Accession No. F 07228 (Published Feb. 15, 1995), Auffray, C., et al.
Expressed Sequence Tags Database Accession No. HSU 71092 (Published Dec. 21, 1996), Kolakowski, L.F. Jr., et al.
Expressed Sequence Tags Database Accession No. AF 008650 (Published Oct. 1, 1997). Lakaye. B., et al.
GenEmbl Accession No. Q99705, Kolakowski, L.F. Jr., et al., published Nov. 1, 1997.
GenEmbl Accession No. P97639. Lakaye, B., et al., published Nov. 1, 1997.
Expressed Sequence Tags Database Accession No. Z 86090 (Published Feb. 22, 1997), Lloyd, D.
Expressed Sequence Tags Database Accession No. T 30384 (Published Sep. 13, 1996), Bergsma, DJ., et al.
Expressed Sequence Tags Database Accession No. V 28115 (Published Sep. 25, 1998), Bergsma, DJ., et al.
Auffray, C., et al. IMAGE: intégration au niveau moléculaire de l'analyse du gé nome humain et de son expression.C.R. Acad. Sci.Paris, Sci. Vie(1995) 318:263-272.
Burgaud, J., et al., “Melanin-concentrating hormone binding sites in human SVK 14 keratinocytes,” (1997) 241(3): 622-629.
Borowsky, B., et al. “Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist”Nature Medicine(2002) 8(8): 825-830.
Chambers, C., et al., Melanin-concentrating hormone is the cognate ligand for the orphan G-pro coupled receptor SLC-1Nature(Jul. 15, 1999) 400:261-265.
Kolakowski, L.F.. et al. Characterization of a human gene related to genes encoding somatostatin receptors. FEBS Letters (1996) 398: 253-258.
Lakaye, B., et al., Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene.Biochimica et Biophysica Acta(Feb. 4, 1998) 1401(2): 216-220.
Rudiger, et al., “Single-Molecule Detection Technologies in Miniaturized High Throughput Screening: Binding Assays for G-Protein-Coupled Receptors Using Fluorescence Intensity Distribution Analysis and Fluorescence Anistotropy,”Journ of Biomol Screening(2001) 6(1): 29-37.
Saito, Y., et al. Molecular characterization of the melanin-concentrating-hormone receptor.Nature(Jul. 15, 1999) 400: 265-268.
Shimada, M., et al. Mice lacking melanin-concentrating hormone receptor are hypophagic and lean.Nature(Dec. 17, 1998) 396: 670-674.
Drozdz et al., 1995, “Melanin-concentrating hormone binding to mouse melanoma cells in vitro.” FEBS Letters, vol. 359, pp. 199-202.
Matsunaga et al., 1989, “Melanin Concentrating Hormone (MCH): Synthesis and Bioactivity Studies of MCH Fragment Analogues.” Peptides, vol. 10, pp. 349-354.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of identifying melanin concentrating hormone... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of identifying melanin concentrating hormone..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of identifying melanin concentrating hormone... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3947926

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.